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GenomicsThe Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse ChIP-seq]
Purpose: To characterize the genome-wide distribution of H3K79me2 in murine MN1 driven myeloid leukemia Methods: We performed Chip-seq for the H3K79me2 in leukemias isolated from moribund mice that had been injected with common myeloid progenitors (CMPs) transduced with MSCV-MN1-GFP Results: H3K79me...
ORGANISM(S): Mus musculus 
2016-01-12 | E-GEOD-76746 | biostudies-arrayexpress
GenomicsTumor suppressor role of Ezh2 in an NRASQ61K driven model of Early T-cell Precursor Acute Lymphoblastic Leukemia (ChIP-Seq)
Purpose: To characterize changes in genome-wide H3K27me3 associated with homozygous inactivation the Polycomb Repressive Complex 2 (PRC2) lysine methyltransferase Ezh2 in a mouse model of earlt T-cell precursor ALL (ETP-ALL) Methods: We performed Chip-seq for the H3K27me3 Chromatin mark on Ezh2ff an...
ORGANISM(S): Mus musculus 
2016-01-07 | E-GEOD-76601 | biostudies-arrayexpress
TranscriptomicsProspective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating precision medicine (PMed) trials
Feasibility trial to examine the ability to conduct molecular guided therapy in a geographically distributed systems within strict time constraints Canine patients were enrolled across a broad panel of tumor types where tumor samples were acquired and processed to preserve RNA quality for genomic an...
ORGANISM(S): Canis lupus 
2014-04-28 | E-GEOD-51131 | biostudies-arrayexpress
UnknownGlobal disparities in SARS-CoV-2 genomic surveillance.
Not available
S-EPMC9667854 | biostudies-literature
UnknownAnalysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.
Not available
S-EPMC4564951 | biostudies-literature
UnknownEdetate Disodium-Based Chelation for Patients With a Previous Myocardial Infarction and Diabetes: TACT2 Randomized Clinical Trial.
Not available
S-EPMC11325247 | biostudies-literature
UnknownMultivitamins After Myocardial Infarction in Patients With Diabetes: A Randomized Clinical Trial.
Not available
S-EPMC11877407 | biostudies-literature
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