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The Tuba8 gene was identified as a CAR-regulated gene that was induced during phenobarbital (PB) promotion of liver tumor. TUBA8 was then over-expressed in heaptocarcinoma cells to determine the function of TUBA8. First, identify genes that are regulated by CAR and are induced during liver tumor dev...
ORGANISM(S): Mus musculus 
Zone 1 and zone 3 areas were captured from mouse liver sections by laser capture microdissection Total RNA was isolated and gene expression profiles were determined using microarrays Six C3H/HeNCrlBR (C3H) mice, 3 male and 3 female mice were used. They were not treated in any way.
ORGANISM(S): Mus musculus 
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