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TranscriptomicsTranscription profiling of human chronic lymphocytic leukemia samples and pRS-15/16 transfected MEG01 cell lines to identify MiR-15a and miR-16-1 cluster function in human leukemia
Two samples obtained from the MEG01 cell line transfected with pRS-15/16 and pRS-E vector, each one in triplicate, and 16 CLL samples were analyzed by microarray using Human Genome U133A Plus 2.0 GeneChip arrays (Affymetrix).
ORGANISM(S): Homo sapiens 
2008-06-01 | E-MEXP-1482 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human normal prostate and prostate cancer samples to investigate the role of miRNA involvement in prostate carcinogenesis
MicroRNA (miRNA) expression profiles for prostate cancers were examined to investigate the miRNA involvement in prostate carcinogenesis. miRNA microarray analysis identified statistical unique profiles, which could discriminate prostate cancers from noncancerous prostate tissues.
ORGANISM(S): Homo sapiens 
2005-12-31 | E-TABM-49 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human normal stomach and gastric cancer samples to investigate the role of miRNA involvement in stomach carcinogenesis
MicroRNA (miRNA) expression profiles for gastric cancers were examined to investigate the miRNA involvement in stomach carcinogenesis. miRNA microarray analysis identified statistical unique profiles, which could discriminate stomach cancers from noncancerous stomach tissues.
ORGANISM(S): Homo sapiens 
2005-12-31 | E-TABM-50 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human normal lung and lung cancer samples to investigate the role of miRNA involvement in lung carcinogenesis
MicroRNA (miRNA) expression profiles for lung cancers were examined to investigate the miRNA involvement in lung carcinogenesis. miRNA microarray analysis identified statistical unique profiles, which could discriminate lung cancers from noncancerous lung tissues.
ORGANISM(S): Homo sapiens 
2005-12-31 | E-TABM-47 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human normal colon and colon cancer samples to investigate the role of miRNA involvement in colon carcinogenesis
MicroRNA (miRNA) expression profiles for colon cancers were examined to investigate the miRNA involvement in colon carcinogenesis. miRNA microarray analysis identified statistical unique profiles, which could discriminate colon cancers from noncancerous colon tissues.
ORGANISM(S): Homo sapiens 
2005-12-31 | E-TABM-46 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human colorectal cancer samples with CpG island methylator phenotype (CIMP)
The CpG island methylator phenotype (CIMP) in colorectal tumors can be recognized by an increased frequency of aberrant methylation in a specific set of genomic loci. Because of the strong association of CIMP with high microsatellite instability (MSI-H), the identification of CIMP+ tumors within mi...
ORGANISM(S): Homo sapiens 
2008-01-01 | E-TABM-328 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human chronic lymphocytic leukemia samples to identify whether microRNA profiles are prognostic indicators
MicroRNA expression profiles can distinguish normal B cells from malignant B cells in chronic lymphocytic leukemia (CLL). We investigated whether microRNA profiles are associated with known prognostic factors in CLL. We evaluated the microRNA expression profiles of 94 samples of CLL cells for which ...
ORGANISM(S): Homo sapiens 
2005-10-27 | E-TABM-41 | biostudies-arrayexpress
TranscriptomicsEwing's sarcoma miRNA expression
MicroRNA profile of 34 EWS by microarray
ORGANISM(S): Homo sapiens 
2011-06-15 | E-TABM-1100 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast cancer cell lines and tissue samples to identify aberrant microRNA expression
MicroRNAs are a class of small non-coding RNAs that control gene expression by targeting messenger RNAs and triggering either translation repression or RNA degradation. Their aberrant expression may be involved in human diseases, including cancer. Indeed, microRNA aberrant expression has been previo...
ORGANISM(S): Homo sapiens 
2006-01-01 | E-TABM-23 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human colorectal cancer samples with high microsatellite instability
Background. Colorectal cancer develops through two main genetic instability pathways characterized by distinct pathologic features and clinical outcome. Results. We investigated colon cancer samples (23 characterized by microsatellite stability, MSS, and 16 by high microsatellite instability, MSI-H)...
ORGANISM(S): Homo sapiens 
2007-09-07 | E-TABM-326 | biostudies-arrayexpress
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