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TranscriptomicsGenome-wide analysis of alternative splicing in Caenorhabditis elegans
Alternative splicing (AS) plays a crucial role in the diversification of gene function and regulation. Consequently, the systematic identification and characterization of temporally regulated splice variants is of critical importance to understanding animal development. We have used high-throughput ...
ORGANISM(S): Caenorhabditis elegans 
2010-12-14 | E-GEOD-25927 | biostudies-arrayexpress
GenomicsAnalysis of Blimp-1 and Irf-1 genomic binding in wild type and Prdm1/Blimp-1 mutant embryonic gut
The goal of this study was to profile Blimp1 binding in E18.5 small intestine using a Blimp-1-eGFP knock-in allele, and to compare Blimp-1-eGFP genomic binding with Irf-1 genomic binding in normal small intestine. Changes in Irf-1 binding between wild type and Prdm1/Blimp-1 mutant small intestine w...
ORGANISM(S): Mus musculus 
2015-07-10 | E-GEOD-66069 | biostudies-arrayexpress
GenomicsSetdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing
Purpose: The aim of this study is (1) to identify the chromatin occupancy of the epigenetic regulator Setdb1 in mouse embryonic fibroblasts (MEF); (2) to profile key epigenetic marks H3K9me2, H3K9me3 and H3K27me3; utilizing wildtype cells with nonsilencing shRNA mediated knockdown and Setdb1 geneTra...
ORGANISM(S): Mus musculus 
2016-05-18 | E-GEOD-66522 | biostudies-arrayexpress
UnknownAre individual differences in appetitive and defensive motivation related? A psychophysiological examination in two samples.
Not available
S-EPMC3962705 | biostudies-literature
UnknownVertebrate-class-specific binding modes of the alphavirus receptor MXRA8.
Not available
S-EPMC10615782 | biostudies-literature
ProteomicsProteogenomic analysis of chemo-refractory high grade serous ovarian cancer
To improve our understanding of the molecular basis of chemo-refractory high grade serous ovarian cancers (HGSOCs), we characterized the proteogenomic landscape of 242 (refractory and sensitive) HGSOCs, representing one discovery and two independent validation cohorts (spanning four academic centers...
ORGANISM(S): Homo Sapiens 
PXD040742 | panorama
GenomicsOCAC OncoArray data
Germline genotype data on 56,479 ovarian cancer cases and controls
EGAD00010001192 | EGA
GenomicsThe Ovarian Cancer Association Consortium OncoArray genome-wide association study
A custom Illumina genotyping array, the OncoArray. The array includes a genome-wide backbone, comprising 230,000 SNPs tagging most common genetic variants, together with dense mapping of known susceptibility regions, rare variants from sequencing experiments, pharmacogenetic markers, and cancer-rela...
EGAS00001002305 | EGA
GenomicsThe Ovarian Cancer Association Consortium Data Access Committee
Data Access Committee EGAC00001000616
EGAC00001000616 | EGA
UnknownDe novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Not available
S-EPMC7007577 | biostudies-literature
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