Genome-wide analysis of alternative splicing in Caenorhabditis elegans

ABSTRACT: Alternative splicing (AS) plays a crucial role in the diversification of gene function and regulation. Consequently, the systematic identification and characterization of temporally regulated splice variants is of critical importance to understanding animal development. We have used high-throughput RNA sequencing and microarray profiling to analyze AS in C. elegans across various stages of development. This analysis identified thousands of novel splicing events, including hundreds of developmentally regulated AS events. To make these data easily accessible and informative, we constructed the C. elegans Splice Browser, a web resource in which researchers can mine AS events of interest and retrieve information about their relative levels and regulation across development. The data presented

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Qun Pan 

PROVIDER: E-GEOD-25927 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress