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TranscriptomicsCultured Cyto and Syncytio-trophoblast samples exposed to varying degrees of hypoxia (methylation)
The mechanisms by which the placenta adapts to exogenous stimuli to create a stable and healthy environment for the growing fetus are not well known. Low oxygen tension and sub-optimal vitamin D levels influence placental function and both are associated with preeclampsia, a condition associated wit...
ORGANISM(S): Homo sapiens 
2013-01-18 | E-GEOD-41336 | biostudies-arrayexpress
TranscriptomicsCultured Cyto and Syncytio-trophoblast samples exposed to varying degrees of hypoxia (expression)
The mechanisms by which the placenta adapts to exogenous stimuli to create a stable and healthy environment for the growing fetus are not well known. Low oxygen tension and sub-optimal vitamin D levels influence placental function and both are associated with preeclampsia, a condition associated wit...
ORGANISM(S): Homo sapiens 
2013-01-18 | E-GEOD-41331 | biostudies-arrayexpress
TranscriptomicsRNA-seq of hypoxic and normoxic soybean roots (cultivars: Embrapa 45 and BR 4)
RNA-sequencing of twelve treatments: two cultivars (Embrapa 45 and BR 4), two oxygen conditions [fully aerobic state (normoxy) and hypoxic], and three treatment sampling times (0.5h, 4h, and 28h). For each of twelve treatments, equimolar quantities of purified total RNA from roots of twelve plants [...
ORGANISM(S): Glycine max 
2017-11-21 | E-MTAB-5709 | biostudies-arrayexpress
TranscriptomicsComparison of Normal Prostate Fibroblasts Overexpressing Cyclin D1 and Carcinoma Associated Fibroblasts
The cyclin D1 oncogene encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the Rb protein and promotes progression through G1 to S phase of the cell cycle. Several prostate cancer cell lines and a subset of primary prostate cancer samples have increased cyclin D1 prote...
ORGANISM(S): Homo sapiens 
2007-08-31 | E-GEOD-6936 | biostudies-arrayexpress
TranscriptomicsProstate Cancer Gene Expression Changes after Treatment with Neoadjuvant Dutasteride
To identify molecular changes underlying the chemopreventive or tumor promoting effects of SRD5A inhibition, we profiled gene expression changes in benign prostate epithelium from patients with PCa treated with dutasteride, a dual SRD5A inhibitor. Subjects were aged 45-80 years with clinically local...
ORGANISM(S): Homo sapiens 
2008-12-01 | E-GEOD-9972 | biostudies-arrayexpress
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
UnknownResistance Analyses of HCV NS3/4A Protease and NS5B Polymerase from Clinical Studies of Deleobuvir and Faldaprevir.
Not available
S-EPMC4975400 | biostudies-literature
TranscriptomicsExpression data from Control, AKT and RAS transduced cells
Mutations in both RAS and the PTEN/PIK3CA/AKT signaling module are found in the same human tumors. PIK3CA and AKT are downstream effectors of RAS, and the selective advantage conferred by mutation of two genes in the same pathway is unclear. Based on a comparative molecular analysis, we show that ac...
ORGANISM(S): Homo sapiens 
2013-03-19 | E-GEOD-45276 | biostudies-arrayexpress
UnknownEarly High-Dose Vitamin D3 for Critically Ill, Vitamin D-Deficient Patients.
Not available
S-EPMC7306117 | biostudies-literature
TranscriptomicsGenomic landscape of meningiomas: genotyping
Meningiomas are one of the most common adult brain tumors. For most patients, surgical excision is curative. However, up to 20% recur. Currently, the molecular determinants predicting recurrence and malignant transformation are lacking. We performed global genetic and genomic analysis of 85 meni...
ORGANISM(S): Homo sapiens 
2011-10-11 | E-GEOD-16583 | biostudies-arrayexpress
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