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Podocyte injury is a major cause of chronic kidney disease, but the involved signaling pathways are largely unknown. Here, we used ultrasensitive proteomics to investigate the response of the native renal podocyte to injury and prioritized candidates by aligning proteinuria in individual mice with p...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-07-29 | PXD012025 | Pride
Examined the expression effects of supplementing Drosophila food on heart and nephrocyte complexes 30 female flies fed standard diet supplemented with 0.1 M glucosamine were dissected in cold ADH, and heart/nephrocyte complexes were harvested and analyzed. Animals were pre-fed glucosamine or sucrose...
ORGANISM(S): Drosophila melanogaster 
Examined the expression effects of supplementing Drosophila food on heart and nephrocyte complexes 30 female flies fed standard diet supplemented with 0.1 M glucosamine were dissected in cold ADH, and heart/nephrocyte complexes were harvested and analyzed.
ORGANISM(S): Drosophila melanogaster 
2015-06-12 | GSE69815 | GEO
We assessed the functional role of the cell polarity protein Bazooka on nephrocyte function. Here, we did a proteomics anaylsis of isolated garland nephrocytes from 3rd install larvae. Analysis of the data identified several differentially regulated proteins.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-07-07 | PXD018635 | Pride
Expression array of glucosamine-fed Drosophila heart/nephrocyte complexes
Podocyte injury is a major cause of chronic kidney disease, but the involved signaling pathways are largely unknown. Here, we used ultrasensitive proteomics to investigate the response of native podocytes from mice with Doxorubicin-induced injury. We observed perturbations of known propagating pathw...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-29 | PXD012064 | Pride
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