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UnknownAlteration of the Nucleotide Excision Repair (NER) Pathway in Soft Tissue Sarcoma.
Not available
S-EPMC9369086 | biostudies-literature
UnknownAssociation between NER Pathway Gene Polymorphisms and Wilms Tumor Risk.
Not available
S-EPMC6118157 | biostudies-literature
TranscriptomicsExpression changes in Caenorhabditis elegans xpa-1 mutant
Background: The ability of an organism to repair DNA damage is implicated in carcinogenesis and aging. Interestingly expression profiling of Nucleotide Excision Repair (NER) deficient segmental progeroid mice revealed gene expression changes resembling these observed in aged wild type animals. Our p...
ORGANISM(S): Caenorhabditis elegans 
2013-05-03 | E-GEOD-39252 | biostudies-arrayexpress
GenomicsThe yeast GG-NER complex evicts histone H2A.Z-containing barrier nucleosomes from CID boundaries during DNA repair
Background: Repair of DNA damage requires chromatin remodeling to permit removal of the lesions. How nucleosomes are remodelled to initiate repair of DNA damage remains largely unknown. Here, we describe how chromatin is altered during repair of UV-induced DNA damage at the level of the linear organ...
ORGANISM(S): Saccharomyces cerevisiae 
2018-12-06 | E-MTAB-6569 | biostudies-arrayexpress
UnknownPolymorphisms of multiple genes involved in NER pathway predict prognosis of gastric cancer.
Not available
S-EPMC5217006 | biostudies-literature
TranscriptomicsTranscription profiling of liver from Csbm/m/Xpa-/- knockout mice to investigate the effect of nucleotide excision repair pathway inactivation
Cockayne syndrome (CS) is a photosensitive, DNA repair disorder associated with progeria caused by a defect in the transcription-coupled repair (TCR) subpathway of nucleotide excision repair (NER). Here, complete inactivation of NER in Csbm/m/Xpa-/- mutants causes a phenotype that reliably mimics th...
ORGANISM(S): Mus musculus 
2007-01-01 | E-MEXP-835 | biostudies-arrayexpress
ProteomicsStructural basis of TFIIH activation for nucleotide excision repair
Nucleotide excision repair (NER) is the major DNA repair pathway that removes UV-induced and bulky DNA lesions. There is currently no structure of NER intermediates, which form around the large multisubunit transcription factor IIH (TFIIH). Here we report the cryo-EM structure of an NER intermediate...
ORGANISM(S): Homo sapiens (Human) 
2019-07-02 | PXD013947 | Pride
Ner pathway Bs3 cross-linking 
TranscriptomicsRoles for the Transcription Elongation Factor NusA in Both DNA Repair and Damage Tolerance Pathways in Escherichia coli
Here we report our observations that have led us to propose that the transcription elongation factor NusA promotes a novel class of transcription-coupled repair (TCR) in addition to its previously proposed role in recruiting translesion synthesis (TLS) DNA polymerases to gaps encountered during tran...
ORGANISM(S): Escherichia coli 
2010-07-14 | E-GEOD-22829 | biostudies-arrayexpress
UnknownAssociation of NER pathway gene polymorphisms with susceptibility to laryngeal cancer in a Chinese population.
Not available
S-EPMC4637715 | biostudies-literature
UnknownAssociation between NER pathway gene polymorphisms and neuroblastoma risk in an eastern Chinese population.
Not available
S-EPMC7851491 | biostudies-literature
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