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MetabolomicsIntegration of metabolomics, genomics and immune phenotypes reveals the causal roles of metabolites in disease

BACKGROUND: Recent studies highlight the role of metabolites in immune diseases, but it remains unknown how much of this effect is driven by genetic and non-genetic host factors.

RESULT: We systematically investigate circulating metabolites in a cohort of 5...

2021-06-14 | MTBLS2633 | MetaboLights
UnknownBacillus Calmette-Guerin vaccination as defense against SARS-CoV-2 (BADAS): a randomized controlled trial to protect healthcare workers in the USA by enhanced trained immune responses.
Not available
S-EPMC10548680 | biostudies-literature
UnknownInduction of Trained Innate Immunity in Human Monocytes by Bovine Milk and Milk-Derived Immunoglobulin G.
Not available
S-EPMC6213000 | biostudies-literature
UnknownGenetic diversity of lactase persistence in East African populations.
Not available
S-EPMC4700599 | biostudies-literature
UnknownMultivariate inference of pathway activity in host immunity and response to therapeutics.
Not available
S-EPMC4176341 | biostudies-literature
ProteomicsEpitope shaving and fungal immune evasion – cell wall proteomes
The cell wall provides a major physical interface between fungal pathogens and their mammalian host. This extracellular armour is critical for fungal cell homeostasis and survival. Yet essential cell wall moieties, such as β-1,3-glucan, are recognised as pathogen-associated molecular patterns (PAMPs...
ORGANISM(S): Candida albicans (Yeast) 
2020-06-15 | PXD018027 | Pride
Candida albicans Lc-msms Cell wall 
UnknownDNA hypermethylation during tuberculosis dampens host immune responsiveness.
Not available
S-EPMC7260034 | biostudies-literature
TranscriptomicsTranscription profiling of human monocyte-derived dendritic cells exposed to pathogenic and harmless fungi
To ditinguish different immune response and investigate the rule of proper recognition of fungi, a transcriptional analysis on moDCs exposed to a pathogenic and a harmless fungi was performed. Monocyte-derived dendritic cells were treated with Candida albicans, two different forms of Saccaromyces ce...
ORGANISM(S): Homo sapiens 
2010-03-22 | E-MTAB-135 | biostudies-arrayexpress
ProteomicsEpitope shaving and fungal immune evasion – culture supernatants
The cell wall provides a major physical interface between fungal pathogens and their mammalian host. This extracellular armour is critical for fungal cell homeostasis and survival. Yet essential cell wall moieties, such as β-1,3-glucan, are recognised as pathogen-associated molecular patterns (PAMPs...
ORGANISM(S): Candida albicans (Yeast) 
2020-06-15 | PXD018044 | Pride
Candida albicans Lc-msms Secretome 
UnknownGenome-Wide Association Study Identifies Novel Colony Stimulating Factor 1 Locus Conferring Susceptibility to Cryptococcosis in Human Immunodeficiency Virus-Infected South Africans.
Not available
S-EPMC7686661 | biostudies-literature
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