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MetabolomicsMetabolic adaptation of diatoms to hypersalinity

Microalgae are important primary producers and form the basis for the marine food web. As global climate changes, so do salinity levels that algae are exposed to. A metabolic response of algal cells partly alleviates the resulting osmotic stress. Some metabolites involved in the response are well...

2023-09-04 | MTBLS3177 | MetaboLights
UnknownA molecular fragment cheminformatics roadmap for mesoscopic simulation.
Not available
S-EPMC4212157 | biostudies-literature
UnknownGenomic diversity and relationship analyses of endangered German Black Pied cattle (DSN) to 68 other taurine breeds based on whole-genome sequencing.
Not available
S-EPMC9875303 | biostudies-literature
MetabolomicsComparison of singlequad and Orbitrap mass analyzer coupled to gas chromatography reveals potential of high resolution GC MS for untargeted metabolomics

The development of improved spectrometers and supporting computational tools is expected to eventually enable the rapid annotation of whole metabolomes. However, rarely are novel mass spectrometers directly compared to the previously used ones in the field of metabolomics, thus preventing researc...

2020-01-24 | MTBLS1104 | MetaboLights
ProteomicsThe previously uncharacterized YlxR (RnpM) protein modulates the activity of ribonuclease P
Even though Bacillus subtilis is one of the most studied organisms, no function has been identified for about 20% of its proteins. Among these unknown proteins are several RNA- and ribosome-binding proteins suggesting that they exert functions in cellular information processing. In this work, we hav...
ORGANISM(S): Bacillus subtilis 
2024-06-16 | PXD043900 | Pride
Bacillus subtilis Protein-rna crosslinking 
MetabolomicsStrong effect of Penicillium roqueforti populations on volatile and metabolic compounds responsible for aromas, flavour and texture in blue cheeses
Studies of food microorganism domestication can provide important insight into adaptation mechanisms and lead to commercial applications. Penicillium roqueforti is a fungus with four genetically differentiated populations, two of which were independently domesticated for blue cheese-making, with the...
2021-10-06 | MTBLS1509 | MetaboLights
UnknownWhole-Genome Sequencing Data Reveal New Loci Affecting Milk Production in German Black Pied Cattle (DSN).
Not available
S-EPMC10048491 | biostudies-literature
MetabolomicsAn Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors
Direct infusion high-resolution mass spectrometry (DIHRMS) is a novel, high-throughput approach to rapidly and accurately profile hundreds of lipids in human serum without prior chromatography, facilitating in-depth lipid phenotyping for large epidemiological studies to reveal the detailed associati...
2024-02-02 | MTBLS4461 | MetaboLights
UnknownThe previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis in vitro.
Not available
S-EPMC10853771 | biostudies-literature
MetabolomicsSubcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remains the world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of multidrug therapy. Difficulty visualizing the subcellular localization of antibiotics in infected host cells means t...
2020-12-07 | MTBLS959 | MetaboLights
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