Neural progenitor

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Unknown (3771)
Transcriptomics (2417)
Genomics (2207)
Proteomics (127)
Other (96)
Methylation profiling (41)
Metabolomics (16)
Models (2)
Genomic (1)

Organisms

Homo sapiens (1469)
Mus musculus (1310)
Rattus norvegicus (66)
Danio rerio (40)
Drosophila melanogaster (30)
Gallus gallus (23)
Xenopus laevis (18)
Pan troglodytes (15)
Arabidopsis thaliana (12)
Saccharomyces cerevisiae (11)
synthetic construct (11)
Bos taurus (10)
Macaca fascicularis (7)
Macaca mulatta (7)
Sus scrofa (4)
Papio anubis (4)
Schmidtea mediterranea (3)
Rhodospirillum rubrum (2)
Malus domestica (2)
Staphylococcus aureus (2)
Ambystoma mexicanum (2)
Nothobranchius furzeri (2)
Pan paniscus (2)
Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74 (1)
Mus musculus castaneus (1)
Capra hircus (1)
Mus musculus musculus (1)
Monodelphis domestica (1)
Medicago truncatula (1)
Zea mays (1)

Organisms

Homo sapiens (709)
Mus musculus (693)
Rattus norvegicus (25)
Danio rerio (22)
Drosophila melanogaster (17)
Gallus gallus (15)
Xenopus laevis (8)
Xenopus tropicalis (4)
Macaca mulatta (4)
Bos taurus (3)
Gorilla gorilla gorilla (2)
Mustela putorius furo (2)
Pan troglodytes (2)
Schmidtea mediterranea (2)
Mus (2)
Kryptolebias marmoratus (1)
Rattus rattus (1)
Tupaia belangeri chinensis (1)
Papio anubis (1)
Ciona robusta (1)
Ambystoma mexicanum (1)
Mus musculus musculus (1)
Canis lupus familiaris (1)
unidentified (1)

Repository

ENA (1745)
biostudies-arrayexpress (1515)
geo (1444)
pride (75)
EGA (49)
MassIVE (25)
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iProX (10)
jPOST (9)
LINCS (9)
ExpressionAtlas (4)
PanoramaPublic (4)
GPMDB (3)
GNPS (2)
BioModels (1)
Cell Collective (1)
dbGaP (1)

Tissue

Cell culture (33)
Brain (14)
Neural progenitor cell (13)
Neuronal stem cell (9)
Embryonic stem cell (7)
Pluripotent stem cell (5)
Stem cell (5)
Cell suspension culture (3)
Epithelial cell (3)
Multipotent stem cell (3)
Embryo (2)
HEK-293 cell (2)
Neuron of cerebral cortex (2)
Astrocyte of the cerebral cortex (1)
Blood (1)
Bone marrow (1)
Brain macroglial cell (1)
Cerebral cortex neuron (1)
Embryonic cell (1)
Embryonic cerebral cortex (1)
Fibroblast (1)
Generation of neurons (1)
Glioblastoma cell (1)
Hepatoma cell line (1)
Hippocampal neuron (1)
Larval brain (1)
Liver (1)
Neural stem cell (1)
Neuron (1)
Permanent cell line cell (1)

Disease

Normal (13)
Parkinson's disease (4)
Disease free (4)
Not Available (3)
Glioblastoma (2)
Neuroblastoma (2)
Breast cancer (2)
Leigh disease (2)
Rett syndrome (2)
Zika virus congenital syndrome (2)
Astrocytoma (1)
MAS (1)
SMARD1 (1)
Peripheral neuropathy (1)
Breast Carcinoma (1)
Myeloid neoplasm (1)
Oligodendroglioma (1)
Familial dysautonomia (1)
Giant Cell Glioblastoma (1)
Megakaryoblastic leukaemia (1)
Acute Myeloid Leukemia (1)
Chronic myelogenous leukemia (1)
Astrocytoma III (1)
None (1)
Carcinoma (1)
Central nervous system cancer (1)
Alexander disease (1)
Brain glioblastoma multiforme (1)
Generalized convulsive epilepsy (1)
Mucinous pancreas adenocarcinoma (1)

Technology Type

Mass Spectrometry (75)
Shotgun proteomics (37)
Bottom-up proteomics (16)
Affinity purification coupled with mass spectrometry proteomics (10)
Mass spectrometry (9)
Mass spectrometry (9)
Data-dependent acquisition (8)
Gel-based experiment (6)
GCP (5)
Mass spectrometry assay (5)
Data-independent acquisition (5)
P100 (4)
Top-down proteomics (3)
SWATH MS (2)
NextSeq 500, Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, ILLUMINA (1)
All-ion fragmentation (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
HDMSE (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (85)
Illumina HiSeq 2500 (42)
NextSeq 500 (32)
Illumina HiSeq 2000 (22)
Illumina HiSeq 4000 (19)
N/A (8)
Illumina HiSeq 1500 (7)
NextSeq 550 (7)
Illumina NovaSeq X (6)
NextSeq 2000 (5)
Chromium Next GEM Single Cell Multiome ATAC + Gene Expression Reagent Bundle, (4)
Illumina Genome Analyzer IIx (4)
Qubit 4.0 Fluorometer/ Agilen 5300 Fragment Analyzer (3)
10X Genomics reagent kit (3)
10X Chromium Nuclei Isolation Kit (2)
Chromium 10x (2)
Sony SH800 (2)
Affymetrix Fluidics Station 400 (2)
NA (2)
DNBSEQ-G400 (2)
Illumina HiSeq 1000 (2)
DNBSEQ-T7 (2)
HiSeq X Ten (2)
BD Influx Cell Sorter (1)
Chromium X instrument (10x Genomics); GEM-X FX Chips (10x Genomics); Agilent TapeStation D1000; qPCR (library quantification kit for Illumina platforms) (1)
Chromium X instrument (10x Genomics); GEM-X Flex Sample Preparation v2 Kit (10x Genomics; 1000781); Human Gene Expression Probe Set v1.0.1 (10x Genomics) (1)
Countess 3 FL Automated Cell Counter (Thermo Fisher Scientific; AMQAF2000); GEM-X Flex Sample Preparation v2 Kit (10x Genomics; 1000781) (1)
TruSeq Stranded Total RNA kit (Illumina) (1)
In-house Perl scripts (1)
Chromium Controller, 10x Genomics and Chromium X, 10x Genomics (1)

Publication Date

2014 (238)
2025 (228)
2015 (220)
2013 (216)
2026 (200)
2016 (200)
2021 (187)
2022 (171)
2023 (168)
2012 (167)
2024 (165)
2010 (140)
2011 (125)
2019 (121)
2018 (116)
2020 (114)
2017 (100)
2008 (92)
2009 (68)
2007 (37)
2005 (12)
2006 (11)
2004 (4)

CHEBI ID

CHEBI:15428 (5)
CHEBI:16811 (4)
CHEBI:6650 (4)
CHEBI:16335 (4)
CHEBI:16467 (4)
CHEBI:15891 (4)
CHEBI:18012 (4)
CHEBI:30769 (4)
CHEBI:78679 (3)
CHEBI:16113 (3)
CHEBI:16675 (3)
CHEBI:17822 (3)
CHEBI:26271 (3)
CHEBI:49033 (3)
CHEBI:16040 (3)
CHEBI:22653 (3)
CHEBI:18186 (3)
CHEBI:17234 (3)
CHEBI:28300 (3)
CHEBI:18257 (3)
CHEBI:17533 (3)
CHEBI:16708 (3)
CHEBI:16668 (3)
CHEBI:16750 (3)
CHEBI:15746 (3)
CHEBI:28875 (3)
CHEBI:16958 (3)
CHEBI:16610 (3)
CHEBI:15741 (3)
CHEBI:28044 (3)

Metabolite Name

Uridine (4)
Succinic acid (3)
Methionine (3)
Arginine (3)
Asparagine (3)
Serine (3)
Alanine (3)
Glutamine (3)
Glucose (3)
Glutamic acid (3)
Inosine (3)
PE 42:4 (2)
PC 44:6 (2)
PI 38:2 (2)
PC 30:3 (2)
PI 36:2 (2)
PI 36:1 (2)
PI 38:4 (2)
PC 42:5 (2)
PC 42:4 (2)
PC 28:1 (2)
PE 36:4 (2)
PE 42:8 (2)
PE 42:7 (2)
PE 42:5 (2)
PE 40:9 (2)
PE 40:8 (2)
PE 40:6 (2)
PE 40:4 (2)
PE 38:7 (2)

IsPrivate

False (1)

First Public Date

2025 (227)
2024 (184)
2023 (180)
2026 (164)
2021 (153)
2022 (149)
2014 (144)
2020 (107)
2019 (105)
2018 (95)
2017 (93)
2015 (61)
2016 (53)
2013 (30)

Modelling Approach

Ordinary differential equation model (1)

Study type

Transcription profiling by array (832)
RNA-seq of coding RNA (253)
ChIP-seq (113)
RNA-seq of coding RNA from single cells (60)
Methylation profiling by array (40)
Other (19)
Methylation profiling by high throughput sequencing (19)
Comparative genomic hybridization by array (17)
RNA-seq of non coding RNA (16)
Unknown experiment type (13)
ChIP-chip by tiling array (12)
Cell line - High-throughput sequencing (12)
RNA-seq of total RNA (11)
Transcription profiling by SAGE (9)
DNA-seq (9)
ChIP-chip by array (7)
ATAC-seq (7)
Single nucleus RNA sequencing (7)
Genotyping by array (6)
MicroRNA profiling by array (6)
Animal - High-throughput sequencing (5)
Transcription profiling by RT-PCR (5)
ScATAC-seq (5)
Cell line - Single-cell sequencing (4)
Baseline (2)
Proteomic profiling by array (2)
CUT&RUN (2)
ChIP-chip by SNP array (1)
FAIRE-seq (1)
Differential (1)

Release Date

2014 (382)
2021 (364)
2023 (353)
2020 (350)
2015 (348)
2016 (346)
2022 (323)
2025 (308)
2013 (304)
2024 (291)
2018 (273)
2019 (257)
2017 (253)
2012 (249)
2010 (209)
2011 (208)
2008 (128)
2009 (122)
2026 (76)
2007 (59)
2006 (33)
2005 (21)
2004 (14)
2003 (6)
2001 (4)
2002 (3)
1999 (1)

Lab affiliation

CCBIO, Department of Clinical Medicine, Faculty of Medicine, University of Bergen, Bergen, Norway (2)
Department of Molecular Systems Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran (2)
Director, Translational Proteomics Research Unit, IRCM Director, Biomarker Pipeline for Precision Medicine Strategic Initiative Full IRCM Research Professor Full Research Professor, Department of Biochemistry and Molecular Medicine (accreditation for the Molecular Biology Programs), Université de Montréal Holder of the Bell-Bombardier Chair of Excellence Person in charge of responsible conduct of research, IRCM (2)
1. Ministry of Education Key Laboratory of Biosystems Homeostasis & Protection, College of Life Sciences, Zhejiang University, Hangzhou, China 2. Cancer Center, Zhejiang University, Hangzhou, China (1)
1Centre for Bioscience, Manchester Metropolitan University, Manchester, UK (1)
Assistant Professor of Neurosurgery Department of Neurosurgery Houston Methodist Research Institute Weill Cornell Medical College (1)
Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China (1)
Brain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA (1)
Cedars-Sinai Medical Center (1)
Center for Molecular Neurobiology Hamburg (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany (1)
Center for Proteomics & Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA (1)
Children's Medical Research Insitute, The University of Sydney (1)
Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (1)
Core Facility Proteomics - ZBSA - Freiburg University (1)
Department of Anatomy and Neurobiolog; Department of Pharmacology, Physiology and Biophysics; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, 02118, USA (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biology, Quantitative Proteomics Group, Interfaculty Institute of Cell Biology, University of Tübingen, Tübingen, Germany (1)
Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich Heine University, Medical Faculty, Düsseldorf, Germany (1)
Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands. (1)
Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands (1)
Department of Molecular Neuropathology, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico (1)
Department of Neuroscience University of Connecticut School of Medicine (1)
Department of Pharmacology | UW School of Medicine Institute of Stem Cell and Regenerative Medicine | University of Washington, Seattle, USA (1)
Department of Proteomics and Chromatin Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, The Netherlands (1)
Department of Structural and Molecular Biology IBMB-CSIC Barcelona, Spain (1)
Dept. Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands (1)
Dept. of Medical Biochemistry and Cell Biology Institute of Biomedicine The Sahlgrenska Academy at the University of Gothenburg SWEDEN (1)
Developmental Neurobiology, Max Planck Institute of Psychiatry, Munich, Germany (1)
Dr. Elke Hammer Universitätsmedizin Greifswald Interfakultäres Institut für Genetik und Funktionelle Genomforschung Abteilung für Funktionelle Genomforschung Felix-Hausdorff-Straße 8 17487 Greifswald Germany (1)
Duke-NUS Medical School, Singapore. Department of Neuroscience, Department of Neurology, School of Medicine and Public Health, Waisman Center, University of Wisconsin, USA. (1)

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Elevated lysophosphatidylcholines during SSRI-induced neural differentiation correlate with early neurodevelopmental symptoms

Background: Selective serotonin reuptake inhibitors (SSRIs) are often prescribed during pregnancy. Yet, epidemiological studies link in-utero SSRI exposure with neurodevelopmental disorders, such as autism and ADHD. The potential molecular mechanisms by which SSRIs impact early n...

2026-04-02 | MTBLS12645 | MetaboLights

Transcriptome analysis of mouse cerebral cortical neural progenitor cells

Transcriptome analysis of neural progenitor/stem cells is limited by the lack of a reliable method for cell isolation. We have designed a genetic dual reporter strategy that can allow prospective isolation of cortical neural progenitor cells and their neuronal progeny form the same animals. These ce...

ORGANISM(S): Mus musculus

2011-09-19 | E-GEOD-22946 | biostudies-arrayexpress

TRIM28 silences endogenous retroviruses in neural progenitor cells

Here we show that in neural progenitor cells (NPCs) TRIM28 silences transcription of two groups of endogenous retroviruses (ERVs): IAP1 and MMERVK10C. Derepression of ERVs in Trim28-deficient NPCs was associated with a loss of H3K9me3 and resulted in transcriptional upregulation and reverse transcri...

ORGANISM(S): Mus musculus

2015-01-07 | E-GEOD-45930 | biostudies-arrayexpress

CD133/CD140a-Based Isolation of Distinct Human Multipotent Neural Progenitor Cells and Oligodendrocyte Progenitor Cells

The mechanisms underlying the specification of oligodendrocyte fate from multipotent neural progenitor cells (NPCs) in developing human brain are unknown. In this study, we sought to identify antigens sufficient to distinguish NPCs free from oligodendrocyte progenitor cells (OPCs). We investigated t...

ORGANISM(S): Homo sapiens

2013-04-23 | E-GEOD-40676 | biostudies-arrayexpress

mRNA-Seq and microRNA-Seq whole-transcriptome analysis of rhesus monkey ESC neural differentiation revealed the potential rosette neural stem cell regulators

Rosette neural stem cells (R-NSCs) represent early stage of neural development and possess full neural differentiation and regionalization capacities. R-NSCs are considered as stem cells of neural lineage and have important implications in study of neurogenesis and cell replacement therapy. However,...

ORGANISM(S): Macaca mulatta

2014-07-03 | E-GEOD-53260 | biostudies-arrayexpress

Defining a developmental path to neural fate by global expression profiling of mouse ESCs and adult NS cells

Defining a developmental path to neural fate by global expression profiling of mouse embryonic stem cells and adult neural stem/progenitor cells. This SuperSeries is composed of the following subset Series: GSE4075: Neural induction (Embrioid bodies-Retinoic acid) GSE4076: Neural induction (N2B27 m...

ORGANISM(S): Mus musculus

2010-06-11 | E-GEOD-4082 | biostudies-arrayexpress

Prospective Identification, Isolation, and Profiling of a Telomerase-Expressing Subpopulation of Human Neural Stem Cells, using sox2 Enhancer-Directed Fluorescence-Activated Cell Sorting

Sox2 is expressed by neural stem and progenitor cells, and a sox2 enhancer identifies these cells in the forebrains of both fetal and adult transgenic mouse reporters. We found that an adenovirus encoding EGFP placed under the regulatory control of a 0.4 kb sox2 core enhancer selectively identified ...

ORGANISM(S): Homo sapiens

2011-02-25 | E-GEOD-27505 | biostudies-arrayexpress

Generation of neural progenitor cells by chemical cocktails and hypoxia

Neural progenitor cells (NPCs) can be induced from somatic cells by defined factors. Here we report that NPCs can be generated from mouse embryonic fibroblasts by a chemical cocktail, namely VCR (V, VPA, an inhibitor of HDACs; C, CHIR99021, an inhibitor of GSK-3 kinases and R, Repsox, an inhibitor o...

ORGANISM(S): Mus musculus

2015-04-27 | E-GEOD-68311 | biostudies-arrayexpress

ChIP-seq analysis of H3K9 acetylation enrichment in hESCs and day 8 neural progenitor cells

H3K9 acetylation was enriched in pluripotency genes in hESCs and in neural genes in neural progenitor cells Examination of H3K9 acetylation distributions in hESCs and neural progenitor cells

ORGANISM(S): Homo sapiens

2015-03-11 | E-GEOD-66778 | biostudies-arrayexpress

Microarray of neural progenitor cells from neonatal lung injury mice treated with placebo or umbilical-cord mesenchymal stromal cell extracellular vesicles or untreated, as well as age-matched control mice

The purpose of this experiment was to determine the transcriptional differences between neural progenitor cells from neonatal lung injury mice vs. control mice, as well as neonatal lung injury mice treated with umbilical-cord mesenchymal stromal cell extracellular vesicles vs. neonatal lung injury m...

ORGANISM(S): Mus musculus

2022-05-17 | E-MTAB-11157 | biostudies-arrayexpress

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