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ProteomicsSoluble SORLA enhances neurite outgrowth and regeneration through activation of EGFR and MAPK pathways
SORLA is a type I transmembrane component associated with Alzheimers disease (AD) risk. Although SORLA is abundantly expressed in neurons, physiological roles for SORLA remain yet unclear. Here, we show that cultured neurons overexpressing SORLA (SORLA TG) feature enhanced neurite length, and accele...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-05-12 | MSV000085400 | MassIVE
UnknownPromoting the Outgrowth of Neurites on Electrospun Microfibers by Functionalization with Electrosprayed Microparticles of Fatty Acids.
Not available
S-EPMC7758907 | biostudies-literature
ProteomicsHerpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and facilitate neuroinfection
Herpes simplex virus type 1 (HSV-1) is a highly contagious and prevalent human pathogen that causes many diseases, including encephalitis. During primary infection, HSV-1 infects epithelial cells and then neurites of peripheral neurons, establishing lifelong infection in the neuronal cell body. Neur...
ORGANISM(S): Homo sapiens (Human) 
2024-01-06 | PXD039569 | Pride
Herpes simplex virus Neuroinfection Neurite outgrowth Extracellular vesicles 
UnknownPTEN modulates neurites outgrowth and neuron apoptosis involving the PI3K/Akt/mTOR signaling pathway.
Not available
S-EPMC6797942 | biostudies-literature
UnknownEngraving the Surface of Electrospun Microfibers with Nanoscale Grooves Promotes the Outgrowth of Neurites and the Migration of Schwann Cells.
Not available
S-EPMC7487060 | biostudies-literature
ProteomicsGrowth cone localization of the mRNA encoding a chromatin regulator modulates neurite outgrowth
Neurons exploit local mRNA translation and retrograde transport of transcription factors to regulate gene expression in response to signaling events at distal neuronal ends. Whether epigenetic factors could also be involved in such regulation is not known. We report that the mRNA encoding the HMGN5 ...
ORGANISM(S): Mus musculus (Mouse) 
2015-04-17 | PXD001070 | Pride
Hmgn5 Neuronal development Chromatin regulation 
UnknownTriggering of high-speed neurite outgrowth using an optical microheater.
Not available
S-EPMC4645119 | biostudies-literature
UnknownNeurite outgrowth involves adenomatous polyposis coli protein and beta-catenin.
Not available
S-EPMC3373789 | biostudies-literature
UnknownNetrin-1 stimulates developing GnRH neurons to extend neurites to the median eminence in a calcium- dependent manner.
Not available
S-EPMC3467286 | biostudies-literature
UnknownHerpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Not available
S-EPMC10865794 | biostudies-literature
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