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TranscriptomicsMicroarray Expression Analysis of 3 Canonical Toxoplasma infections of human neuroepithelial cells
The outcome of infections with Toxoplasma gondii in humans is dependent in part on the genetic makeup of the infecting organism. Recent studies have indicated that most infecting Toxoplasma organisms fall into 1 of 3 canonical lineages. Previous studies have investigated the effects of Toxoplasma ...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-22986 | biostudies-arrayexpress
GenomicsThe tumor suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements
In Drosophila, defects in asymmetric cell division can result in the formation of stem cell derived tumors. Here, we reveal a different mechanism that can result in the formation of very similar terminal brain tumor phenotypes. We demonstrate that brain tumors in l(3)mbt mutants originate from overp...
ORGANISM(S): Drosophila melanogaster 
2011-08-29 | E-GEOD-29206 | biostudies-arrayexpress
GenomicsEpigenome analysis of low-grade neuroepithelial tumors with FGFR2 fusions
Epigenome analysis of low-grade neuroepithelial tumors with FGFR2 fusions
PRJNA721967 | ENA
GenomicsEpigenome analysis of low-grade neuroepithelial tumors with FGFR1 alterations
Epigenome analysis of low-grade neuroepithelial tumors with FGFR1 alterations
PRJNA639971 | ENA
TranscriptomicsDNA methylation data from CNS-PNETs and various other brain tumor samples
Primitive neuroectodermal tumours of the central nervous system (CNS PNETs) are highly aggressive, poorly differentiated embryonal tumours occurring predominantly in young children. Using DNA methylation and gene expression profiling we have demonstrated that a significant proportion of institutiona...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-73801 | biostudies-arrayexpress
GenomicsNew Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs
Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly aggressive, poorly differentiated embryonal tumors occurring predominantly in young children but also affecting adolescents and adults. Herein we demonstrate that a significant proportion of institutionally diagnos...
EGAS00001001632 | EGA
TranscriptomicsGene expression data from CNS-PNETs and various other brain tumor samples
Primitive neuroectodermal tumors of the central nervous system (CNS PNETs) are highly aggressive, poorly differentiated embryonal tumors occurring predominantly in young children. Using DNA methylation and gene expression profiling we have demonstrated that a significant proportion of institutionall...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-73038 | biostudies-arrayexpress
GenomicsThe evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion
Astroblastomas are rare brain tumours which predominate in children and young adults, and have a controversial claim as a distinct entity, with no established WHO grade. Reports suggest a better outcome than high grade gliomas, though they frequently recur. Recently, they have been described to over...
EGAS00001002432 | EGA
Methylation profilingEpigenome analysis of low-grade neuroepithelial tumors with FGFR2 fusions
Genome-wide DNA methylation profiling of 8 low-grade neuroepithelial tumors (LGNET) with FGFR2 fusions with various histologic diagnoses including ganglioglioma, multinodular and vacuolating neuronal tumor (MVNT), low-grade glioneuronal tumor NOS, and polymorphous low-grade neuroepithelial tumor of ...
ORGANISM(S): Homo sapiens 
2021-07-27 | GSE172081 | GEO
Methylation profilingEpigenome analysis of low-grade neuroepithelial tumors with FGFR1 alterations
Genome-wide DNA methylation profiling of 30 low-grade neuroepithelial tumors with FGFR1 alterations including rosette-forming glioneuronal tumor, pilocytic astrocytoma, dysembryoplastic neuroepithelial tumor, and extraventricular neurocytoma. The Illumina Infinium EPIC 850k Human DNA Methylation Bea...
ORGANISM(S): Homo sapiens 
2020-08-19 | GSE152653 | GEO
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