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TranscriptomicsWhole transcriptome analysis of FACS purified somatosensory neuron subtypes and whole dorsal root ganglia tissue
The goal of this study was to analyze global gene expression in specific populations of somatosensory neurons in the periphery, including major, non-overlapping populations that include nociceptors, pruriceptors, and prorioceptors. The mammalian somatosensory nervous system encodes the perception of...
ORGANISM(S): Mus musculus 
2014-12-23 | E-GEOD-55114 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
We sequenced mRNA from individual stormal cells (Macrophages, Monocytes, and Neutrophils) and tumor epithelial cells from KrasG12dD; p53-/- murine lung cancer model and WT control mouse to compare gene expressio profiles of lung cancer stroma and tumor cells to their counterparts of WT lugns. The tu...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-59831 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profile and splicing events of iPS-derived motorneurons from SMA patient, unaffected father and TGC-treated cells
Spinal Muscular Atrophy (SMA) is an autosomal recessive motor neuron disease and is the second most common genetic disorder leading to death in childhood. Motoneurons derived from induced pluripotent stem cells (iPSC) obtained by reprogramming SMA patient and his healthy father fibroblasts, and gene...
ORGANISM(S): Homo sapiens 
2013-01-04 | E-GEOD-27205 | biostudies-arrayexpress
Transcriptomics1,25-dihydroxyvitamin D3-induced genes in mouse mixed neuron-glial cell cultures
Transcriptomic response of mouse mixed neuron-glial cell cultures to 1,25-dihydroxyvitamin D3 6 samples are analysed with three biological replicates in two conditions, control versus 1,25-dihydroxyvitamin D3 (1,25(OH)2D3)
ORGANISM(S): Mus musculus 
2013-03-25 | E-GEOD-41184 | biostudies-arrayexpress
TranscriptomicsRapid reprogramming of primary human astrocytes into potent tumor initiating cells with defined genetic factors
Cancer stem cells play key roles in human malignancies. However, their cellular and molecular origins are still poorly understood. Here we report the successful generation of cancer stem cells from primary human astrocytes by use of defined genetic factors. Combined transduction of four factors —m...
ORGANISM(S): Homo sapiens 
2016-11-07 | E-MTAB-4771 | biostudies-arrayexpress
GenomicsDirect transdifferentiation of tumorigenic melanoma cells to non-tumorigenic neuron-like cells
Direct transdifferentiation of tumorigenic melanoma cells to non-tumorigenic neuron-like cells
PRJNA1020415 | ENA
UnknownNeuron-Glial Interactions in Health and Brain Cancer.
Not available
S-EPMC9845196 | biostudies-literature
GenomicsDirect transdifferentiation of tumorigenic melanoma cells to non-tumorigenic neuron-like cells (methylation)
Direct transdifferentiation of tumorigenic melanoma cells to non-tumorigenic neuron-like cells (methylation)
PRJNA1021235 | ENA
GenomicsSensory neurons drive pancreatic cancer progression through glutamatergic cancer-neuron pseudo-synapses.
Sensory neurons drive pancreatic cancer progression through glutamatergic cancer-neuron pseudo-synapses.
PRJNA1255578 | ENA
GenomicsSensory neurons drive pancreatic cancer progression through glutamatergic cancer-neuron pseudo-synapses
Sensory neurons drive pancreatic cancer progression through glutamatergic cancer-neuron pseudo-synapses
PRJNA1235799 | ENA
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