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MetabolomicsGinsenoside Rg5 protects against hypoxic neuronal injury
For metabolome analysis, major metabolic intermediates were analyzed with technical support from Applied Protein Technology Co., Ltd. (Shanghai, China) 17. Briefly, eight treated and untreated cell samples stored in liquid nitrogen were processed and separated by ultrahigh-performance liquid chromat...
2026-07-14 | MTBLS15037 | MetaboLights
GenomicsMicroglial Trem2 shapes neuronal bioenergetics during development
Microglial Trem2 shapes neuronal bioenergetics during development
PRJNA1047066 | ENA
ProteomicsAbnormalities of mitochondrial dynamics and bioenergetics in neuronal cells from CDKL5 deficiency disorder
CDKL5 deficiency disorder (CDD) is a rare neurodevelopmental disorder caused by pathogenic variants in the Cyclin-dependent kinase-like 5 (CDKL5) gene, resulting in dysfunctional CDKL5 protein. It predominantly affects females and causes seizures in the first few months of life, ultimately resulting...
ORGANISM(S): Homo sapiens (Human) 
2025-04-28 | PXD063372 | Pride
Cdkl5  cdkl5 deficiency disorder  induced pluripotent stem cell  mitochondria  oxidative phosphorylation  proteomics. 
ProteomicsLow glucose culture conditions alter neuronal energetics, mimicking in vivo studies
Neurons are almost exclusively cultured in media containing glucose at much higher concentration than found in the brain. To test whether “standard” hyperglycaemic culture conditions affect neuronal respiration compared to near- euglycemic conditions, we grew neuronal cultures with minimal glial con...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-30 | PXD059008 | Pride
Primary mouse neuron Cell culture Glucose Mitochondrial respiration Neurobasal media Neuronal bioenergetics 
GenomicsNPAS3-regulated astrocyte mitochondria bioenergetics is required for cognition
NPAS3-regulated astrocyte mitochondria bioenergetics is required for cognition
PRJNA1148481 | ENA
UnknownAn iPSC-derived neuronal model reveals manganese's role in neuronal endocytosis, calcium flux and mitochondrial bioenergetics.
Not available
S-EPMC12410566 | biostudies-literature
UnknownPhotobiomodulation promotes repair following spinal cord injury by restoring neuronal mitochondrial bioenergetics via AMPK/PGC-1α/TFAM pathway
Not available
S-EPMC9512226 | biostudies-literature
ProteomicsMitochondrial inorganic polyphosphate (polyP) is a contributor towards maintaining cellular bioenergetics in SH-SY5Y cells: a proteomics and metabolomics approach
Inorganic polyphosphate (polyP) is an ancestral, ubiquitous, and well-conserved polymer, which is present in all the studied organisms. It is formed by individual subunits of orthophosphate which are linked together by bonds structurally similar and isoenergetic to those found in ATP. While the meta...
ORGANISM(S): Homo Sapiens 
2022-03-16 | PXD028185 | panorama
UnknownAdverse effects of Δ9-tetrahydrocannabinol on neuronal bioenergetics during postnatal development.
Not available
S-EPMC7714410 | biostudies-literature
UnknownNeuronal induction and bioenergetics characterization of human forearm adipose stem cells from Parkinson's disease patients and healthy controls.
Not available
S-EPMC8923468 | biostudies-literature
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