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Background A Boolean network is a simple computational model that may provide insight into the overall behavior of genetic networks and is represented by variables with two possible states (on/off), of the individual nodes/genes of the network. In this study, a Boolean network model has been used t...
ScRNAseq - Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration
Co-targeting neurotransmitter signaling and CDK9 to treat diffuse midline glioma [ATAC-Seq]
Co-targeting neurotransmitter signaling and CDK9 to treat diffuse midline glioma [CUT&RUN]
Co-targeting neurotransmitter signaling and CDK9 to treat diffuse midline glioma [RNA-seq]
Aberrant neurotransmitter signaling and transcriptional dysregulation are hallmarks of glioma and represent potential therapeutic targets. In this study, we uncover mechanisms of crosstalk between monoamine neurotransmitter signaling and transcriptional regulation in diffuse midline glioma (DMG) tha...
ORGANISM(S): Homo sapiens 
2026-04-24 | GSE317726 | GEO
Aberrant neurotransmitter signaling and transcriptional dysregulation are hallmarks of glioma and represent potential therapeutic targets. In this study, we uncover mechanisms of crosstalk between monoamine neurotransmitter signaling and transcriptional regulation in diffuse midline glioma (DMG) tha...
ORGANISM(S): Homo sapiens 
2026-04-24 | GSE317370 | GEO
Aberrant neurotransmitter signaling and transcriptional dysregulation are hallmarks of glioma and represent potential therapeutic targets. In this study, we uncover mechanisms of crosstalk between monoamine neurotransmitter signaling and transcriptional regulation in diffuse midline glioma (DMG) tha...
ORGANISM(S): Homo sapiens 
2026-04-24 | GSE317354 | GEO
We use cerebral organoid fusions and a novel migration tracking platform to understand the functional impact of neurotransmitter signaling on migrating human interneurons.
ORGANISM(S): Homo sapiens 
2021-10-20 | GSE161550 | GEO
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