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MetabolomicsDysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multi-drug resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to control infection including zinc stres...

2022-02-23 | MTBLS318 | MetaboLights
UnknownEvaluation of Time-Limited Trials Among Critically Ill Patients With Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments.
Not available
S-EPMC8042568 | biostudies-literature
UnknownImplementation and evaluation of the 3 Wishes Project in safety-net hospitals: Protocol for a hybrid effectiveness-implementation study.
Not available
S-EPMC12047788 | biostudies-literature
UnknownEnd-of-Life Care During the Coronavirus Disease 2019 Pandemic: The 3 Wishes Program.
Not available
S-EPMC8505331 | biostudies-literature
TranscriptomicsIdentification of transcripts whose abundance changes in response to acute switches in DSX isoform
RNAseq of dissected adult fat body after DSX isoform is switched using temperature inducible alleles or constructs. Biological duplicates were sequenced for each genotype at each condition.
ORGANISM(S): Drosophila melanogaster 
2014-10-30 | E-GEOD-55848 | biostudies-arrayexpress
GenomicsIdentifying targets of DSX with DamID-seq
We have adapted the DamID protocol for use with high throughput sequencing. We have used DamID to identify the positions within the Drosophila genome where the transcription factor DSX is bound. We sequenced DpnI-digested genomic DNA from fly tissues containing UAS-Dam (control) or UAS-Dam-DsxF or ...
ORGANISM(S): Drosophila melanogaster 
2014-10-30 | E-GEOD-27269 | biostudies-arrayexpress
UnknownPhase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III.
Not available
S-EPMC2854625 | biostudies-literature
UnknownFly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly.
Not available
S-EPMC8944923 | biostudies-literature
UnknownExome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.
Not available
S-EPMC6534468 | biostudies-literature
UnknownMeta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
Not available
S-EPMC7515840 | biostudies-literature
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