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Newcastle disease (ND) is an acute, febrile, and highly contagious disease caused by the virulent Newcastle disease virus (vNDV) worldwide. The disease causes serious economic losses to the poultry industry. However, the metabolic changes caused by vNDV infection remain unclear. The objective of thi...
2019-12-20 | MTBLS1115 | MetaboLights

A549 cells were infected with NDV at a multiplicity of infection (MOI) of 3 at 37°C, and the cells were collected 24 hours post-infection.

2025-11-05 | MTBLS13267 | MetaboLights
Airway epithelial cells from 3 different breeds of chicken infected with Newcastle Disease virus were sequenced and compared to cells from uninfected control birds. The 3 breeds were an indigenous breed, commercial Rhode Island Reds and a hybrid breed (Kenbro).
ORGANISM(S): Gallus gallus 
This study aimed to characterize differential responses between the relatively resistant (Fayoumi) and susceptible (Leghorn) chicken lines when challenged with a high titered lentogenic Newcastle Disease Virus (NDV) strain via the eyes and nostrils at three weeks of age. The trachea epithelial cells...
ORGANISM(S): Gallus gallus 
The dendritic cell (DC) is a master regulator of immune responses. Pathogenic viruses subvert normal immune function in DCs through the expression of immune antagonists. Understanding how these antagonists interact with the host immune system requires knowledge of the underlying genetic regulatory n...
ORGANISM(S): Homo sapiens 
Newcastle Disease virus infection in chickens
Transposon mutagenesis screening of Newcastle disease virus (NDV)
This study aimed to characterize differential responses between the relatively resistant (Fayoumi) and susceptible (Leghorn) chicken lines when challenged with a high titered lentogenic Newcastle Disease Virus (NDV) strain via the eyes and nostrils at three weeks of age. The lung was collected from ...
ORGANISM(S): Gallus gallus 
Whole genomic sequence analysis of NDVs distributed in Ethiopia
Nuclear localization of cytoplasmic RNA virus proteins mediated by intrinsic nuclear localization signal (NLS) plays essential roles in successful virus replication. We previously reported that NLS mutation in the matrix (M) protein obviously attenuates the replication and pathogenicity of Newcastle...
ORGANISM(S): Cricetidae 
2020-05-22 | PXD018098 | Pride
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