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UnknownAcute inhibition of PMCA4, but not global ablation, reduces blood pressure and arterial contractility via a nNOS-dependent mechanism.
Not available
S-EPMC5783868 | biostudies-literature
UnknownDeletion of the intestinal plasma membrane calcium pump, isoform 1, Atp2b1, in mice is associated with decreased bone mineral density and impaired responsiveness to 1, 25-dihydroxyvitamin D3.
Not available
S-EPMC4772868 | biostudies-literature
UnknownThe tumour suppressor Ras-association domain family protein 1A (RASSF1A) regulates TNF-α signalling in cardiomyocytes.
Not available
S-EPMC4207857 | biostudies-literature
MetabolomicsAssessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches
Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties to increased nitrogen levels was investigated...
2021-04-26 | MTBLS1801 | MetaboLights
UnknownThe plasmamembrane calmodulin-dependent calcium pump: a major regulator of nitric oxide synthase I.
Not available
S-EPMC2198825 | biostudies-literature
UnknownReduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries.
Not available
S-EPMC5595685 | biostudies-literature
MetabolomicsAssessment of human plasma and urine sample preparation for re-producible and high-throughput UHPLC-MS clinical metabolic phenotyping

Clinical metabolic phenotyping employs metabolomics and lipidomics to detect and measure thousands of metabolites and lipids within human samples. This approach aims to identify metabolite and lipid changes between phenotypes (e.g. disease status) that aid understanding of biochemical mechanisms ...

2020-08-06 | MTBLS1465 | MetaboLights
UnknownCardiac hypertrophy or failure? - A systematic evaluation of the transverse aortic constriction model in C57BL/6NTac and C57BL/6J substrains.
Not available
S-EPMC7357793 | biostudies-literature
UnknownPerturbations in cardiac metabolism in a human model of acute myocardial ischaemia.
Not available
S-EPMC8382649 | biostudies-literature
UnknownPMCA4 inhibition does not affect cardiac remodelling following myocardial infarction, but may reduce susceptibility to arrhythmia.
Not available
S-EPMC7810749 | biostudies-literature
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