Sort   by:  
 Page size 
ProteomicsDrosophila NFS1.R77 is required for differential protein complex composition
S-adenosylmethionine (SAM) is the principle biological methyl group donor for a diverse range of substrates. It is synthesised in the cytosolic methionine cycle and shuttled throughout the cell. The mitochondrial SAM (mitoSAM) pool depends on import through the inner-membrane SAMC and supports the m...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-02-22 | PXD019551 | Pride
Nfs1 Drosophila Iron sulphur clusters 
UnknownCysteine desulfurase is regulated by phosphorylation of Nfs1 in yeast mitochondria.
Not available
S-EPMC5858965 | biostudies-literature
UnknownPhosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis.
Not available
S-EPMC8882671 | biostudies-literature
UnknownNFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis.
Not available
S-EPMC5808442 | biostudies-literature
UnknownNFS1, together with FXN, protects cells from ferroptosis and DNA damage in diffuse large B-cell lymphoma.
Not available
S-EPMC12505007 | biostudies-literature
UnknownHippo pathway activation mediates cardiomyocyte ferroptosis to promote dilated cardiomyopathy through downregulating NFS1.
Not available
S-EPMC11968290 | biostudies-literature
UnknownDuring FeS cluster biogenesis, ferredoxin and frataxin use overlapping binding sites on yeast cysteine desulfurase Nfs1.
Not available
S-EPMC8888459 | biostudies-literature
UnknownD-cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1.
Not available
S-EPMC12373508 | biostudies-literature
Genomics
NFS1 inhibition in mice
PRJNA1129102 | ENA
ProteomicsD-Cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1
Selective targeting of cancer cells is a major challenge for cancer therapy. Many cancer cells overexpress the cystine/glutamate antiporter xCT/CD98, a transport system that imports L-cystine to strengthen antioxidant defenses, thereby promoting tumour survival and progression. We have exploited thi...
ORGANISM(S): Homo sapiens (Human) 
2025-09-01 | PXD063479 | Pride
Iron-sulfur cluster Iron-sulfur protein biogenesis Iron homeostasis. Cancer Amino acid 
Sort   by:  
 Page size