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GenomicsNatural genetic variation perturbs collaborative transcription factor binding required for enhancer selection and function
Natural genetic variation between two mouse strains was used as a natural mutagenesis screen to test various aspects of the proposed model for enhancer selection and function. Chromatin marks H3K4me2, H3K27Ac, and transcription factors PU.1, C/EBPa, and p65 were assessed by ChIP-Seq and GRO-Seq and ...
ORGANISM(S): Mus musculus 
2013-10-15 | E-GEOD-46494 | biostudies-arrayexpress
MetabolomicsSponge exhalent seawater contains a unique chemical profile of dissolved organic matter
Sponges are efficient filter feeders, removing significant portions of particulate and dissolved organic matter (POM, DOM) from the water column. While the assimilation and respiration of POM and DOM by sponges and their abundant microbial symbiont communities have received much attention, there is ...
2016-02-01 | MTBLS281 | MetaboLights
UnknownSeven-Month Prostate-Specific Antigen Is Prognostic in Metastatic Hormone-Sensitive Prostate Cancer Treated With Androgen Deprivation With or Without Docetaxel.
Not available
S-EPMC5805480 | biostudies-literature
TranscriptomicsPriming defense genes and metabolites in hybrid poplar by the green leaf volatile cis-3-hexenyl acetate
• Herbivore-induced plant volatiles (HIPVs), in addition to attracting natural enemies of herbivores, can serve a signaling function within plants by acting as wound signals that induce or prime defenses. However, particularly in woody plants, which compounds within HIPV blends are capable of act...
ORGANISM(S): Populus x canadensis 
2010-05-25 | E-GEOD-11955 | biostudies-arrayexpress
UnknownIntense androgen-deprivation therapy with abiraterone acetate plus leuprolide acetate in patients with localized high-risk prostate cancer: results of a randomized phase II neoadjuvant study.
Not available
S-EPMC4226804 | biostudies-literature
ProteomicsDevelopment of a multiplexed platform to study laccases and cellulase activities using nanostructure-initiator mass spectrometry (NIMS)
Lignocellulosic biomass is composed of three major biopolymers: cellulose, hemicellulose and lignin. Although lignin has long been considered a waste product in biomass conversion efforts, its utilization has since been identified as critical to the economic viability of second-generation biofuel pr...
ORGANISM(S): Aspergillus flavus var. oryzae Agaricus bisporus var. bisporus 
2021-09-09 | PXD020215 | Pride
Laccases Multiplex assay Lignin Nims Ghs (glycosyl hydrolases) Enzyme assays 
ProteomicsOccurrence and fate of per/polyfluoroalkyl substances (PFASs) in residential wastewater treated with nitrogen-removing biofilters
Onsite wastewater treatment systems (OWTSs) are designed for the removal of pathogens and nutrients from septic effluent. However, many other contaminants are widespread in wastewater, including pharmaceuticals, personal care products, and other trace organic chemicals. We analyzed per/polyfluoroalk...
ORGANISM(S): Na 
2025-05-21 | MSV000097952 | MassIVE
ProteomicsReproducible Automated Phosphopeptide Enrichment using Magnetic TiO2 and Ti-IMAC
We describe the application of magnetic TiO2 and Ti-IMAC for uniform automated phosphopeptide enrichment. Combining hyper-porous magnetic microspheres with a magnetic particle-handling robot enables rapid (45 minutes), reproducible (r2 = 0.80) and high-fidelity (> 90% purity) phosphopeptide purifica...
ORGANISM(S): Mus musculus (Mouse) 
2014-09-22 | PXD000892 | Pride
Phosphoproteomics automation 
GenomicsFundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer [RRBS]
Genetic and epigenetic alterations are essential for the initiation and progression of human cancer. We previously reported that primary human medulloblastomas showed extensive cancer-specific CpG island DNA hypermethylation in critical developmental pathways. To determine whether genetically engine...
ORGANISM(S): Mus musculus 
2013-10-10 | E-GEOD-45341 | biostudies-arrayexpress
Proteomicsanti-HA IP-MS of Pdzd8-3×HA knock-in mouse neocortex
Pdzd8-3xHA knock-in mice and control littermates at postnatal 10 days were put to sleep using medetomidine hydrochloride, midazolam and butorphanol. Pups were then put on the ice for 5 minutes and exsanguinated by terminal intracardial perfusion with ice-cold 2% paraformaldehyde in PBS. The neocorte...
ORGANISM(S): Mus Musculus (mouse) 
2025-04-18 | PXD052134 | JPOST Repository
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