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TranscriptomicsTranscription profiling of mouse embryonic stem (ES) cells differentiated for 6 days samplesed at 24 hour timepoints (d1-d6) vs undifferentiated cells (d0)
Mouse ES cells were differentiated for 6 days. Undifferentiated cells (d0) were compared to cells harvested at 24 hour timepoints (d1-d6).
ORGANISM(S): Mus musculus 
2005-08-31 | E-MEXP-304 | biostudies-arrayexpress
TranscriptomicsHematopoietic differentiation of human embryonic stem cells - timecourse and d7 CD34 and CD41 fractions
This study aimed to examine gene expression in human ES cells (the RUNX1C GFP reporter line) differentiated towrads hameatopoietic mesoderm in a defined serum free medium. At day 7 of differentiation, the cells were sorted into fractions based on CD34 and CD41 expression and the four fractions analy...
ORGANISM(S): Homo sapiens 
2015-01-13 | E-GEOD-64876 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Tcf3, Oct4 and nanog in mouse embryonic stem cells
Embryonic stem cells have a unique regulatory circuitry, largely controlled by the transcription factors Oct4, Sox2 and Nanog, which generates a gene expression program necessary for pluripotency and self-renewal (Boyer et al. 2005; Loh et al. 2006; Chambers et al. 2003; Mitsui et al. 2003; Nichols ...
ORGANISM(S): Mus musculus 
2008-02-28 | E-TABM-409 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Oct4, Nanog and Suz12 in human and mouse embryonic stem cells to identify promoters for miRNAs
Understanding the transcriptional regulatory circuitry responsible for pluripotency and self-renewal in embryonic stem (ES) cells is fundamental to understanding human development and realizing the therapeutic potential of these cells. The transcription factor Oct4 and the chromatin-modifying Polyc...
ORGANISM(S): Homo sapiens 
2010-12-01 | E-TABM-365 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse embryonic stem cells with Ronin/Thap11 knockout
RNA-seq of Ronin/Thap11 knockout and heterozygous control mouse ES cells to assess the role of Ronin
ORGANISM(S): Mus musculus 
2022-01-31 | E-MTAB-10024 | biostudies-arrayexpress
TranscriptomicsRNA-seq of XTE cells and vesicles, XEN and XEN-like cells, and ES cells
The conventional trophoblast stem cells represent post-implantation extraembryonic ectoderm-like state and not that of pre-implantation trophectoderm, irrespective of their origin. To capture the trophectoderm-like state we established culture conditions that facilitate the co-existence of character...
ORGANISM(S): Mus musculus 
2022-09-13 | E-MTAB-8788 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation genome wide binding sites of Oct4, Sox2, and Nanog in human
The transcription factors Oct4, Sox2, and Nanog have essential roles in early development and are required for the propagation of undifferentiated embryonic stem (ES) cells in culture. To gain insights into transcriptional regulation of human ES cells, we have identified Oct4, Sox2, and Nanog target...
ORGANISM(S): Homo sapiens 
2005-09-23 | E-WMIT-5 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human embryonic stem (ES) cells. Undifferentiated cells of different passage numbers (p19 and p128) were vs cells differentiated in hanging drops for 5 days (d5 embryoid bodies) or expanded on gelatin coated dishes for a further 9 days (d14 embryoid bodies)
Undifferentiated cells of different passage numbers (p19 and p128) were compared to cells differentiated in hanging drops for 5 days (d5 embryoid bodies) or expanded on gelatin coated dishes for a further 9 days (d14 embryoid bodies).
ORGANISM(S): Homo sapiens 
2005-08-31 | E-MEXP-303 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of mouse polycomb group (PcG) proteins in embryonic stem cells
Polycomb group (PcG) proteins are highly conserved from flies to mammals and many of these factors have essential roles in early embryonic development. PcG proteins comprise two multimeric complexes, the Polycomb Repressive complexes 1 and 2 (PRC1 and 2), which have been shown to repress transcript...
ORGANISM(S): Mus musculus 
2006-05-09 | E-WMIT-12 | biostudies-arrayexpress
UnknownThe Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries.
Not available
S-EPMC9397647 | biostudies-literature
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