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MetabolomicsIntegrated transcriptomic and hormonomic insights into cadmium tolerance of a Euglena mutabilis Fungal-Algal-Bacterial (FAB) consortium

Coordinated stress response in E. mutabilis involving early Cd uptake, chloroplast-based detoxification, metabolic buffering via paramylon, suppression of growth-promoting hormones, and community-mediated resilience.

2026-07-14 | MTBLS13259 | MetaboLights
TranscriptomicsIdentification of Myelin-gene Regulatory Factor as a Critical Transcriptional Regulator Required for CNS Myelination
The transcriptional control of CNS myelin gene expression is poorly understood. Here we identify gene model 98, which we have named Myelin-gene Regulatory Factor (MRF), as a transcriptional regulator required for CNS myelination. Within the CNS, MRF is specifically expressed by postmitotic oligodend...
ORGANISM(S): Mus musculus 
2009-05-31 | E-GEOD-15303 | biostudies-arrayexpress
UnknownDesign of a phase IV randomised, double-blind, placebo-controlled trial assessing the ImPact of Residual Inflammation Detected via Imaging TEchniques, Drug Levels and Patient Characteristics on the Outcome of Dose TaperIng of Adalimumab in Clinical Remission Rheumatoid ArThritis (RA) patients (PREDICTRA).
Not available
S-EPMC5855387 | biostudies-literature
TranscriptomicsA Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function Understanding the cell-cell interactions that control CNS development and function has long been limited by the lack of methods to cleanly separate astrocytes, neu...
ORGANISM(S): Mus musculus 
2007-12-30 | E-GEOD-9566 | biostudies-arrayexpress
UnknownPharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers.
Not available
S-EPMC3594886 | biostudies-literature
GenomicsChIP-seq experiment to determine the genomic binding sites of mutant V5-tagged ZFHX2 R1913K protein in a stable-expressing human SH-SY5Y neuroblastoma cell line
A novel missense mutation has been identified in a human pain-insensitive family in the gene ZFHX2. We modelled this mutation in mice by changing the orthologous amino acid and carried out pain behaviour tests in mutant BAC transgenic mice. These showed a phenotype of hyposensitivity to noxious ther...
ORGANISM(S): Homo sapiens 
2018-06-11 | E-MTAB-5651 | biostudies-arrayexpress
UnknownPersonalized Cancer Monitoring Assay for the Detection of ctDNA in Patients with Solid Tumors.
Not available
S-EPMC10590345 | biostudies-literature
GenomicsGenome-wide localization of NF-E2 p45 in mouse primary megakaryocytes.
ChIP-seq assay was performed with anti-p45 antibody using in vitro cultured primary megakaryocytes to identify direct p45 target genes in megakaryocytes. This analysis revealed genes that regulate platelet function, which were not known previously to be p45-regulated. ChIP was performed using a day...
ORGANISM(S): Mus musculus 
2013-11-01 | E-GEOD-42249 | biostudies-arrayexpress
GenomicsAutophagy driven by a master regulator of hematopoiesis
Developmental and homeostatic remodeling of cellular organelles is mediated by a complex process termed autophagy. The cohort of proteins that constitute the autophagy machinery function in a multistep biochemical pathway. Though components of the autophagy machinery are broadly expressed, autophagy...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-GEOD-32491 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of src1 mutant
Gene expression analysis of a src1 yeast strain mutant and wt yeast strain growing in exponential phase in YPD Keywords: genetic modification Transcriptomic analysis of three independent replicates of wt and src1 yeast strain growing in exponential phase
ORGANISM(S): Saccharomyces cerevisiae 
2008-08-26 | E-GEOD-6370 | biostudies-arrayexpress
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