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GenomicsMus musculus strain:C57BL6/J
Mus musculus strain:C57BL6/J Transcriptome or Gene expression
PRJNA1512713 | ENA
TranscriptomicsGenome-wide microRNA expression induced by TNF
We sequenced microRNAs from bone marrow derived macrophages derived from the control (WT) and RBP-J conditional knockout mice (RBP-J KO; Rbpjf/f; LysM Cre). Examination of differential microRNA expression levels induced by TNF as well as regulated by RBP-J in bone marrow derived macrophages.
ORGANISM(S): Mus musculus 
2016-07-22 | E-GEOD-72966 | biostudies-arrayexpress
TranscriptomicsCardiac left ventricles of 12 week-old male C57BL/6J and C57BL/6J-chrY mice
We have reported previously that when chromosome Y (chrY) from the mouse strain C57BL/6J (abbreviated as B) was substituted for that of A/J mice (ChrY), cardiomyocytes from the resulting 'chromosome substitution' C57BL/6J-chrY strain (abbreviated as B.Y) were smaller than that of their C57BL/6...
ORGANISM(S): Mus musculus 
2009-05-01 | E-GEOD-15354 | biostudies-arrayexpress
TranscriptomicsExpression data comparing human DKK1 and control vector transfected murine osteochondrosarcoma cells (MOS-J)
Canonical Wnt signaling controls proliferation and differentiation of osteogenic progenitor cells, and tumor-derived secretion of the Wnt antagonist Dickkopf-1 (Dkk1) is correlated with osteolyses and metastasis in many bone malignancies. However, the role of Dkk1 in the oncogenesis of primary osteo...
ORGANISM(S): Mus musculus 
2012-12-22 | E-GEOD-43112 | biostudies-arrayexpress
GenomicsAnalysis if IGF1-mediated cardioprotection after acute myocardial infarction in C57BL6/J mice
Analysis if IGF1-mediated cardioprotection after acute myocardial infarction in C57BL6/J mice
PRJNA498421 | ENA
UnknownJagged1 Acts as an RBP-J Target and Feedback Suppresses TNF-Mediated Inflammatory Osteoclastogenesis.
Not available
S-EPMC10693321 | biostudies-literature
TranscriptomicsDietary folate depletion and repletion in A/J and C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9242 | biostudies-arrayexpress
TranscriptomicsDynamic binding of RBPJ is determined by Notch signalling status
Notch signalling plays crucial roles in mediating cell fate choices in all metazoans largely by specifying the transcriptional output of one cell in response to a neighbouring cell. The DNA-binding protein RBPJ is the principle effector of this pathway in mammals and together with the transcription ...
ORGANISM(S): Mus musculus 
2013-05-13 | E-GEOD-37184 | biostudies-arrayexpress
GenomicsJBP1-seq: a fast and efficient method for genome-wide profiling of 5hmC
We developed a novel approach, J-binding protein 1 sequencing (JBP1-seq), that combines the benefits of an improved recombinant JBP1 protein, Nextera-based library construction, and nextgeneration sequencing (NGS) for genome-wide profiling of 5-hydroxymethylcytosine (5hmC). Compared with the orig...
ORGANISM(S): Homo sapiens 
2014-11-26 | E-GEOD-61193 | biostudies-arrayexpress
UnknownJ-domain proteins cooperate with Hsp70 to drive multiphase separation of RNA-binding-deficient TDP-43.
Not available
S-EPMC12688062 | biostudies-literature
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