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TranscriptomicsTranscription profiling of human coronary artery endothelial cells treated with ADMA at 2uM (a pathophysiological dose) and 100uM (a pharmacological dose), for 24h
Asymmetric dimethylarginine (ADMA) is a naturally occurring inhibitor of nitric oxide synthesis that accumulates in wide range of diseases associated with endothelial dysfunction and enhanced atherosclerosis. Plasma ADMA has been implicated as a major novel cardiovascular risk factor, but the mechan...
ORGANISM(S): Homo sapiens 
2005-09-01 | E-MEXP-377 | biostudies-arrayexpress
UnknownVitamin D3 repletion versus placebo as adjunctive treatment of heart failure patient quality of life and hormonal indices: a randomized, double-blind, placebo-controlled trial.
Not available
S-EPMC5663043 | biostudies-literature
TranscriptomicsBarley root gene expression during colonisation by Piriformospora indica
The fungal mutualist Piriformospora indica is colonising barley roots thereby mediating various beneficial effects to its host. The interaction is characterised by an initial biotrophic interaction stage which is followed by a cell death-dependent colonisation phase. We used microarrays to identify ...
ORGANISM(S): Hordeum vulgare 
2010-05-19 | E-GEOD-13756 | biostudies-arrayexpress
TranscriptomicsProteomic and transcriptomic analyses of Dhh1 complexes reveals mitochondrial RNP complex association with yeast P-bodies
P-bodies (PB) are cytoplasmic RNP complexes that aggregate into foci when cells are exposed to stress. While the core components and stress response of PB and related RNP granules are conserved, it remains unclear how and why cells assemble mRNP complexes into granule foci during stress. We use mas...
ORGANISM(S): Saccharomyces cerevisiae 
2015-09-16 | E-GEOD-65989 | biostudies-arrayexpress
UnknownAssessing the effectiveness of oxathiapiprolin toward Phytophthora agathidicida, the causal agent of kauri dieback disease.
Not available
S-EPMC10117877 | biostudies-literature
TranscriptomicsDevelopment of a Fluorescence-Activated Cell Sorting Method Coupled with Whole Genome Amplification To Analyze Minority and Trace Dehalococcoides Genomes in Microbial Communities
Dehalococcoides mccartyi are functionally important bacteria that catalyze the reductive dechlorination of chlorinated ethenes. However, these anaerobic bacteria are fastidious to isolate, making downstream genomic characterization challenging. In order to facilitate genomic analysis, a fluorescence...
ORGANISM(S): Dehalococcoides mccartyi 195 
2015-01-31 | E-GEOD-54040 | biostudies-arrayexpress
UnknownLow prevalence of vitamin D deficiency in elderly Afro-Caribbean men.
Not available
S-EPMC3095488 | biostudies-literature
TranscriptomicsMicroRNA profiling of human cholangiocytes in response to interferon-gamma
Cells of a human cholangiocyte cell line (H69) were exposed to 10 ng/ml of IFN-gamma for 8 h. Cells were collected and processed for miRNA array analysis carried out by EXIQON (Denmark).
ORGANISM(S): Homo sapiens 
2009-02-10 | E-MEXP-1906 | biostudies-arrayexpress
GenomicsSequencing Apoptotic DNA Breakpoints
DNA fragmentation is a well-recognized hallmark of apoptosis. However, the precise DNA sequences cleaved during apoptosis triggered by distinct mechanisms remain unclear. We used next-generation sequencing of DNA fragments generated in Actinomycin D-treated human HL-60 leukemic cells to generate a h...
ORGANISM(S): Homo sapiens 
2011-10-15 | E-GEOD-32997 | biostudies-arrayexpress
TranscriptomicsExpression analysis of C. elegans wild-type N2 and rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutants
Investigation of whole genome gene expression level changes in C. elegans rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutant compared to the wild-type N2 strain. The mutants have altered longevity phenotypes. The mutants analyzed in this study are further described in Di Chen, Patrick Wai-...
ORGANISM(S): Caenorhabditis elegans 
2013-11-14 | E-GEOD-52340 | biostudies-arrayexpress
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