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MetabolomicsMetabolomics analysis of liver reveals profile disruption in bovines upon steroid treatment
INTRODUCTION: The surveillance of illegal anabolic practices in bovine meat production is necessary to guarantee consumers’ health. Screening strategies based on the recognition of indirect biological effects are considered by the community as promising tools to overcome some limitations of classica...
2018-05-08 | MTBLS436 | MetaboLights
GenomicsLINE-1 DNA methylation levels in DPPA3 KO overexpressing DPPA3 mutants
DPPA3 mutants were overexpressed using a doxycycline system to identify regions in DPPA3 necessary for DNA methylation maintenance suppression
ORGANISM(S): Mus musculus 
2020-10-22 | E-MTAB-9653 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of 3iL human embryonic stem cells
Human embryonic stem cells (hESCs) are isolated from the inner cell mass of the blastocysts. The pluripotent properties of hESCs enable the derivation of cell-types or tissues of different lineages for potential applications such as therapeutics discovery and regenerative medicine. Even though hES...
ORGANISM(S): Homo sapiens 
2014-12-12 | E-MTAB-2031 | biostudies-arrayexpress
GenomicsAmplicon bisulfite sequencing of LINE-1 elements in TET catalytic mutants and DPPA3 KO ESCs rescued by doxycylin induced overexpression
Tet1, Tet2 and Tet1/Tet2 catalytic mutants as well as DPPA3 KO ESCs harboring a doxycyclin inducible Dppa3 transgene were induced for several days to monitor LINE-1 methylation levels.
ORGANISM(S): Mus musculus 
2020-10-23 | E-MTAB-9654 | biostudies-arrayexpress
TranscriptomicsTETs controls maintenance DNA methylation via the regulation of Dppa3
Dissection of catalytic and non-catalytic functions of Tet1 and Tet2. Transcriptome profiling of wild type, Tet1 catalytic mutants, Tet2 and Tet1/2 catalytic mutant catalytic during EpiLC differentiation.
ORGANISM(S): Mus musculus 
2020-10-05 | E-MTAB-6797 | biostudies-arrayexpress
ProteomicsDeciphering the interplay of aflatoxin B1 and Epstein-Barr virus on the histone landscape in Burkitt Lymphoma cells
Aflatoxin B1 (AFB1), a potent dietary carcinogen, and Epstein-Barr virus (EBV), an oncogenic virus, are both implicated in cancer development, particularly in endemic regions. However, the combined effects of AFB1 exposure and EBV infection on the epigenetic landscape remain poorly understood. This ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-23 | PXD060719 | Pride
Human Epstein-barr virus Aflatoxin b1 Hptms Burkitt lymphoma cells Lc-ms/ms 
UnknownDevelopment and Validation of a Novel LC-MS/MS Method for a TDM-Guided Personalization of HSCT Conditioning with High-Dose Busulfan in Children.
Not available
S-EPMC9953620 | biostudies-literature
UnknownA phase II study to evaluate LY2603618 in combination with gemcitabine in pancreatic cancer patients.
Not available
S-EPMC5312529 | biostudies-literature
UnknownComprehensive analysis of the specificity of transcription activator-like effector nucleases.
Not available
S-EPMC4005648 | biostudies-literature
TranscriptomicsTet1 controls maintenance DNA methylation via the regulation of Dppa3
Dissection of catalytic and non-catalytic functions of Tet1. DNA methylation (RRBS) profiling of wild type, Tet1 knockout and catalytic mutants during EpiLC differentiation.
ORGANISM(S): Mus musculus 
2020-09-30 | E-MTAB-6785 | biostudies-arrayexpress
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