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no omics definedTranscription profiling of human medullary thyroid carcinoma cell line TT sunitinib or vehicle treatment time course
The aim of the study was to identify major gene expression changes associated to sunitinib response in a human medullary thyroid carcinoma (MTC)ﾠmodel.ﾠWe developed an in vitro kinetic microarray study. The humanﾠﾠMTC cell line, the TT cells, were treated with 250 nM sunitinib or vehicle during 1, 3...
ORGANISM(S): Homo sapiens 
2011-02-26 | E-TABM-929 | biostudies-arrayexpress
TranscriptomicsRad51 binding in meiosis after undergoing S phase with different replication programs.
ChIP-on-chip analysis of Rad51 binding in cells induced to undergo synchronous meiosis after growth in continuous nitrogen-rich conditions or after nitrogen depletion. Comparison of pat1-114 cells grown in -N and +N conditions as well as pat1-114 cells with altered Cdc45 levels in -N conditions. pat...
ORGANISM(S): Schizosaccharomyces pombe 
2014-02-20 | E-GEOD-53880 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis Col-0 plants with wild type, arr1-1 knock-out, ARR1 over-expressor and ARR1-SRDX fusion protein over-expressor genotypes treated with 6-Benzyladenine for different lengths of time
Arabidopsis thaliana Col-0 plants and three other genotypes (ARR1 overexpressor, arr1-1 knockout, overexpressor of ARR1-SRDX fusion protein) were grown in liquid media (1/2 MS, 1 g/L sucrose, 0.5 g/L MES, pH 5.7) in a Percival AR-66L growth chamber at 24 oC, 16:8 h day:night cycle, and 100 µE light ...
ORGANISM(S): Arabidopsis thaliana 
2008-08-31 | E-MEXP-689 | biostudies-arrayexpress
TranscriptomicsSingle-Cell Transcriptomics of Acetaminophen-Induced Responses in Human 2D and 3D Liver Microtissues
This study aimed to investigate how liver cell culture architecture influences acetaminophen (APAP)-induced transcriptional responses at single-cell resolution. We used human liver microtissues composed of primary human hepatocytes (PHHs), Kupffer cells (KCs), and hepatic sinusoidal endothelial cell...
ORGANISM(S): Homo sapiens 
2025-09-01 | E-MTAB-15516 | biostudies-arrayexpress
TranscriptomicsFate and State Transitions during Human Blood Vessel Organoid Development: Time Course
Human blood vessel organoids (hBVOs) derived from human pluripotent stem cells have emerged as a novel system to understand human vascular development, model disorders, and develop regenerative therapies. However, it was unclear which molecular states constitute hBVOs and how cells differentiate and...
ORGANISM(S): Homo sapiens 
2025-03-21 | E-MTAB-14807 | biostudies-arrayexpress
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