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UnknownNovel zerumbone-secondary amide hybrids: ultrasonic synthesis, cytotoxic evaluation, molecular docking and <i>in silico</i> ADMET studies.
Zerumbone, along with its various derivatives and structurally related compounds, has attracted significant scientific interest due to its broad-spectrum pharmacological properties, particularly its anticancer potential. In this study, novel zerumbone-secondary amide hybrids were successfully design...
S-EPMC11934104 | biostudies-literature
UnknownEffectiveness of a digital diabetes self-management education and support program in Vietnamese adults with type 2 diabetes.
Diabetes mellitus remains a major global public health challenge. Mobile applications and digital platforms offer innovative opportunities to enhance diabetes self-management. This study aimed to evaluate the impact of diaB, a digitally delivered diabetes self-management education and support (DSMES...
S-EPMC12638764 | biostudies-literature
UnknownNovel hierarchical Mn <sub><i>x</i></sub> O <sub><i>y</i></sub> -functionalized graphene for enhanced visible-light photodegradation performance.
Novel hierarchical Mn x O y -functionalized graphene photocatalysts were successfully synthesized by simultaneous precipitation combined with electrochemical plasma methods. Comprehensive characterization, such as XRD, Raman, FT-IR, XPS, SEM, and TEM results, show...
S-EPMC12481244 | biostudies-literature
UnknownDevelopment of Activity Rules and Chemical Fragment Design for In Silico Discovery of AChE and BACE1 Dual Inhibitors against Alzheimer's Disease.
Multi-target drug development has become an attractive strategy in the discovery of drugs to treat of Alzheimer's disease (AzD). In this study, for the first time, a rule-based machine learning (ML) approach with classification trees (CT) was applied for the rational design of novel dual-target acet...
S-EPMC10142303 | biostudies-literature
UnknownNewly synthesised oxime and lactone derivatives from Dipterocarpus alatus dipterocarpol as anti-diabetic inhibitors: experimental bioassay-based evidence and theoretical computation-based prediction.
Dipterocarpus alatus-derived products are expected to exhibit anti-diabetes properties. Natural dipterocarpol (1) was isolated from Dipterocarpus alatus collected in Quang Nam province, Vietnam; afterwards, 20 derivatives including 13 oxime esters (2 and 3a-3m) and 7 lactones (4, 5, 6a...
S-EPMC9043233 | biostudies-literature
UnknownFactors relating to mortality in septic patients in Vietnamese intensive care units from a subgroup analysis of MOSAICS II study.
Sepsis is the most common cause of in-hospital deaths, especially from low-income and lower-middle-income countries (LMICs). This study aimed to investigate the mortality rate and associated factors from sepsis in intensive care units (ICUs) in an LMIC. We did a multicenter cross-sectional study of ...
S-EPMC8460806 | biostudies-literature
UnknownStability Constant and Potentiometric Sensitivity of Heavy Metal-Organic Fluorescent Compound Complexes: QSPR Models for Prediction and Design of Novel Coumarin-like Ligands.
Industrial wastewater often consists of toxic chemicals and pollutants, which are extremely harmful to the environment. Heavy metals are toxic chemicals and considered one of the major hazards to the aquatic ecosystem. Analytical techniques, such as potentiometric methods, are some of the methods to...
S-EPMC10383909 | biostudies-literature
UnknownThe WHO Enhanced Gonococcal Antimicrobial Surveillance Programme (EGASP) identifies high levels of ceftriaxone resistance across Vietnam, 2023.
Not available
S-EPMC11260586 | biostudies-literature
UnknownThe World Health Organization (WHO) Enhanced Gonococcal Antimicrobial Surveillance Programme (EGASP) reports continuously high levels of ceftriaxone resistance across Viet Nam, 2024.
Not available
S-EPMC12547025 | biostudies-literature
UnknownA community-based strategy to eliminate hepatitis C among people who inject drugs in Vietnam.

Background

Towards hepatitis C elimination among people who inject drugs (PWID), we assessed the effectiveness of a strategy consisting of a community-based respondent-driven sampling (RDS) as wide screening, a simplified and integrated hospital-based care, and prevention of reinfection supp...
S-EPMC10485672 | biostudies-literature
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