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UnknownNewly synthesised oxime and lactone derivatives from Dipterocarpus alatus dipterocarpol as anti-diabetic inhibitors: experimental bioassay-based evidence and theoretical computation-based prediction.
Dipterocarpus alatus-derived products are expected to exhibit anti-diabetes properties. Natural dipterocarpol (1) was isolated from Dipterocarpus alatus collected in Quang Nam province, Vietnam; afterwards, 20 derivatives including 13 oxime esters (2 and 3a-3m) and 7 lactones (4, 5, 6a...
S-EPMC9043233 | biostudies-literature
UnknownA combination of annual and nonannual forces drive respiratory disease in the tropics.

Background

It is well known that influenza and other respiratory viruses are wintertime-seasonal in temperate regions. However, respiratory disease seasonality in the tropics remains elusive. In this study, we aimed to characterize the seasonality of influenza-like illness (ILI) and influenz...
S-EPMC10081429 | biostudies-literature
UnknownDetection of co-infection and recombination cases with Omicron and local Delta variants of SARS-CoV-2 in Vietnam.
The first nationwide outbreak of COVID-19 in Vietnam started in late April 2021 and was caused almost exclusively by a single Delta lineage, AY.57. In early 2022, multiple Omicron variants co-circulated with Delta variants and quickly became dominant. The co-circulation of Delta and Omicron happened...
S-EPMC11190198 | biostudies-literature
UnknownA community-based strategy to eliminate hepatitis C among people who inject drugs in Vietnam.

Background

Towards hepatitis C elimination among people who inject drugs (PWID), we assessed the effectiveness of a strategy consisting of a community-based respondent-driven sampling (RDS) as wide screening, a simplified and integrated hospital-based care, and prevention of reinfection supp...
S-EPMC10485672 | biostudies-literature
UnknownAdjunctive Dexamethasone for Tuberculous Meningitis in HIV-Positive Adults.

Background

Adjunctive glucocorticoids are widely used to treat human immunodeficiency virus (HIV)-associated tuberculous meningitis despite limited data supporting their safety and efficacy.

Methods

We conducted a double-blind, randomized, placebo-controlled trial involving HIV-positi...
S-EPMC7615197 | biostudies-literature
UnknownAwareness and preparedness of healthcare workers against the first wave of the COVID-19 pandemic: A cross-sectional survey across 57 countries.

Background

Since the COVID-19 pandemic began, there have been concerns related to the preparedness of healthcare workers (HCWs). This study aimed to describe the level of awareness and preparedness of hospital HCWs at the time of the first wave.

Methods

This multinational, multicenter...
S-EPMC8694437 | biostudies-literature
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