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MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
UnknownSEPT9: From pan-cancer to lung squamous cell carcinoma.
Not available
S-EPMC11375884 | biostudies-literature
UnknownDNA damage response-related immune activation signature predicts the response to immune checkpoint inhibitors: from gastrointestinal cancer analysis to pan-cancer validation.
Not available
S-EPMC10976329 | biostudies-literature
MetabolomicsNanoinducers-mediated Mitochondria-Selective Degradation Enhance T Cell Immunotherapy Against Multiple Cancers

Cancer immunotherapy utilizing cytotoxic T lymphocytes (CTLs) has demonstrated significant promise in clinical applications, but cancer immunosuppressive mechanisms hamper further progress in T cell immunotherapy. Here we show a correlation between cancer cell mitochondria content and their resis...

2025-03-13 | MTBLS12284 | MetaboLights
TranscriptomicsHistone 4 Lys-20 Mono-Methylation by SET8 Mediates Wnt Target Gene Activation
Histone methylation has an important role in transcriptional regulation. However, unlike H3K4 and H3K9 methylation, the role of H4K20 mono-methylation (H4K20me-1) in transcriptional regulation remains unclear. Here we show that Wnt3a specifically stimulates H4K20 mono-methylation at TBE (TCF-binding...
ORGANISM(S): Homo sapiens 
2010-12-29 | E-GEOD-24708 | biostudies-arrayexpress
UnknownLinking clinical manifestations and causative organisms may provide clues for the treatment of peritoneal dialysis-associated peritonitis.
Not available
S-EPMC11429430 | biostudies-literature
TranscriptomicsWhole genome ChIP/chip tiling of human ES cells for H3K4me3 and H3K27me3
Chromatin immunoprecipitation was performed using monoclonal antibodiesd. DNA was amplified, fluorescently labeled and hybridized to a series of 38 arrays containing a total of 14.6 million 50-mer oligonucleotides Keywords: ChIP-chip hES whole genome Chromatin immunoprecipitated DNA from H3K4me
ORGANISM(S): Homo sapiens 
2007-09-14 | E-GEOD-8463 | biostudies-arrayexpress
TranscriptomicsRetionic acid gene expression time series in human embryonic stem cells
Retinoic acid RA time course experiment: H1 cells(WiCell Research Institute, WA01, Passage40) maintained in TeSR1 were treated with 1uM retinoic acid (RA) in a detailed time course:day0,day0.5,day1,day1.5,day2,day3, day4 and day5 . Total RNA was prepared by usage of the Qiagen RNA extraction kit. m...
ORGANISM(S): Homo sapiens 
2007-09-13 | E-GEOD-8439 | biostudies-arrayexpress
UnknownPanmim: a resource of pan-cancer metastasis immune microenvironment.
Not available
S-EPMC12570596 | biostudies-literature
UnknownPan-cancer analysis of whole genomes.
Not available
S-EPMC7025898 | biostudies-literature
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