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TranscriptomicsRNA sequencing experiment of S. Cerevisiae strain CEN.PK113-7D in four different chemostat conditions
The RNA sequencing experiment was performed in four different chemostat conditions as control for a CAGE sequencing experiment performed in the same conditions using the industrial relevant S. Cerevisiae strain CEN.PK113-7D
ORGANISM(S): Saccharomyces cerevisiae 
2019-01-03 | E-MTAB-6722 | biostudies-arrayexpress
TranscriptomicsCAGE experiment of S. Cerevisiae strain CEN.PK113-7D in four different chemostat conditions
The CAGE experiment was performed in four different chemostat conditions to assess if and how much the Transcription start site landscape changes in the industrial relevant S. Cerevisiae strain CEN.PK113-7D in different conditions. CAGE was also used to obtain accurate TSS annotations for each expre...
ORGANISM(S): Saccharomyces cerevisiae 
2019-01-03 | E-MTAB-6650 | biostudies-arrayexpress
TranscriptomicsGene expression profiling after vaccination with the RTS,S candidate malaria vaccine in a controlled human malaria infection study
RTS,S is the sole candidate vaccine shown to provide protection against infection to malaria-naive adults challenged with mosquito-borne homologous falciparum malaria and protection against infection and clinical and severe disease to volunteers in malaria-endemic Africa who were exposed to diverse ...
ORGANISM(S): Homo sapiens 
2017-04-27 | E-MTAB-4629 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae during prolonged maltose limited cultivation
Prolonged cultivation (>25 generations) of Saccharomyces cerevisiae in aerobic, maltose-limited chemostat cultures led to profound physiological changes. Maltose hypersensitivity was observed when cells from prolonged cultivations were suddenly exposed to excess maltose. This substrate hypersensitiv...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-8897 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae reveaks increasing nadh oxidation reduces overflow metabolism
When the yeast Saccharomyces cerevisiae is subjected to increasing glycolytic fluxes under aerobic conditions, there is a threshold value of the glucose uptake rate at which the metabolism shifts from being purely respiratory to mixed respiratory and fermentative. This shift is characterized by etha...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-14 | E-GEOD-6277 | biostudies-arrayexpress
TranscriptomicsGenome-wide gene expression in response to mating pheromones in S. pombe
Fission yeast cells undergo sexual differentiation in response to nitrogen starvation. In this process haploid M and P cells first mate to form diploid zygotes, which subsequently enter meiosis and sporulate. Prior to mating, M cells secrete M-factor and P-cells secrete P-factor, and these diffusibl...
ORGANISM(S): Schizosaccharomyces pombe 
2007-08-21 | E-GEOD-5323 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae exposed to the sudden addition of glucose - short term perturbation
Study of the short term (within the first 330 seconds) transcriptional response of S.cerevisiae upon a sudden addition of glucose. Experiment Overall Design: Chemostat cultivation – Saccharomyces cerevisiae (CEN PK 113-7D) was cultivated in an aerobic carbon-limited chemostat culture in a 7-litr...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-12 | E-GEOD-3821 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to investigate formaldehyde as source of free-energy during growth on glucose
Previously, it has been demonstrated that formate can be utilized by Saccharomyces cerevisiae as additional energy source using cells grown in a glucose-limited chemostat. Here, we investigated utilization of formaldehyde as co-substrate. Since endogenous formaldehyde dehydrogenase activities were i...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-18 | E-GEOD-8902 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae grown in acetate, ethanol and maltose limited conditions to investigate transcriptional regulation in controlling fluxes in central carbon metabolism
In contrast to batch cultivation, chemostat cultivation allows the identification of carbon source responses without interference by carbon-catabolite repression, accumulation of toxic products, and differences in specific growth rate. This study focuses on the yeast Saccharomyces cerevisiae, grown ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-8895 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae chemostat cultures limiting for carbon, nitrogen, phosphorus, sulfur under aerobic and anaerobic conditions
The goal of this study was to study this interaction by analyzing genome-wide transcriptional responses to four different nutrient-limitation regimes under aerobic and anaerobic conditions in chemostat cultures of S. cerevisiae. This ‘two-dimensional’ approach resulted in a new, robust set of â€...
ORGANISM(S): Saccharomyces cerevisiae 
2007-07-09 | E-GEOD-1723 | biostudies-arrayexpress
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