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ProteomicsHuman cytomegalovirus long non-coding RNA1.2 suppresses extracellular release of the pro-inflammatory cytokine IL-6 by blocking NF-κB activation
Long non-coding RNAs (lncRNAs) are transcripts of more than 200 nucleotides that are not translated into functional proteins. Cellular lncRNAs have been shown to act as regulators by interacting with target nucleic acids or proteins and modulating their activities. We investigated the role of RNA1.2...
ORGANISM(S): Human herpesvirus 5 strain Merlin Homo sapiens (Human) 
2020-07-08 | PXD018328 | Pride
Tprg1l Il-6 Gene regulation Nf-κb Lncrna Transcriptomics Human cytomegalovirus 
ProteomicsViral lncRNA upregulates multiple A+U-richViral lncRNA upregulates multiple A+U-rich transcripts to promote cell motility and viral dissemination transcripts to promote cell motility and viral dissemination
Long non-coding RNAs are frequently associated with broad modulation of gene expression and thus provide the cell with the ability to synchronize entire metabolic processes. We used transcriptomic and proteomic approaches to investigate whether the most abundant human cytomegalovirus-encoded lncRNA,...
ORGANISM(S): Human herpesvirus 5 strain Merlin Homo sapiens (Human) 
2021-07-27 | PXD022277 | Pride
Cell motility Gene regulation Lncrna A+u rich Transcriptomics Human cytomegalovirus Viral dissemination 
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