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How malignant gliomas arise in a mature brain remains a mystery, hindering the development of preventive and therapeutic interventions. We previously showed that oligodendrocyte precursor cells (OPCs) can be transformed into glioma when mutations are introduced perinatally. However, adult OPCs rarel...
ORGANISM(S): Mus musculus 
Cancer results from molecular mutations occurring in specific cell types, thus determining the cell-of-origin is critical for effective cancer treatment. Inferring such information from terminal tumors can be misleading because malignant tumor cells tend to acquire aberrant properties. Animal models...
ORGANISM(S): Mus musculus 
Comprehensive proteomic analysis for human liver microsome and human liver cytosol from 25 individual donors focusing on drug metabolising enzymes with relative quantification with TMTpro.
ORGANISM(S): Homo Sapiens (human) 
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