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ProteomicsGlobal changes in nitration levels and DNA binding profile of Trypanosoma cruzi histones induced by incubation with host extracellular matrix.
Adhesion of T. cruzi trypomastigotes to components of the extracellular matrix (ECM) is an important step in mammalian host cell invasion. We have recently described a significant increase in the tyrosine nitration levels of histones H2A and H4 when trypomastigotes are incubated with components of t...
ORGANISM(S): Trypanosoma cruzi cruzi 
2021-09-09 | PXD016313 | Pride
Histones Tyrosine nitration Trypanosoma cruzi Extracellular matrix 
ProteomicsProteomics analysis of protein tyrosine nitration
Proteomics analysis of protein tyrosine nitration by LC-MS/MS
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2017-07-24 | PXD005320 | Pride
Protein tyrosine nitration Lc-ms/ms 
ProteomicsProteomics analysis of protein tyrosine nitration, part 2
Proteomics analysis of protein tyrosine nitration by LC-MS/MS
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2017-07-24 | PXD006427 | Pride
Immunoaffinity Proteomics  tyrosine nitration  lc-ms/ms 
ProteomicsGM-CSF nitration is a new driver of myeloid suppressor cell activity in tumors
Reactive oxygen species, including RNS, contribute to the control of multiple immune cell functions within the tumor microenvironment (TME). Tumor-infiltrating myeloid cells (TIMs) represent the archetype of tolerogenic cells that actively contribute to dismantle effective immunity against cancer ar...
ORGANISM(S): Glycine max Mus musculus (Mouse) 
2021-10-04 | PXD027049 | Pride
Post-translational modification  tme Reactive nitrogen species  cytokines  immunosuppression 
ProteomicsNitration of Tyrosines In Complement Factor H Domains Alters Its Immunological Activity and Mediates A Pathogenic Role In Age Related Macular Degeneration
Nitrosative stress has been implicated in the pathogenesis of age related macular degeneration (AMD). Tyrosine nitration is a unique type of post translational modification that occurs in the setting of inflammation and nitrosative stress. To date, the significance and functional implications of tyr...
ORGANISM(S): Homo sapiens (Human) 
2017-08-29 | PXD005613 | Pride
Complement factor h Nitrotyrosine Cfh Macular degeneration 
GenomicsGlobal changes in nitration levels and DNA binding profile of Trypanosoma cruzi histones induced by incubation with host extracellular matrix
Adhesion of T. cruzi trypomastigotes to components of the extracellular matrix (ECM) is an important step in mammalian host cell invasion. We have recently described a significant increase in the tyrosine nitration levels of histones H2A and H4 when trypomastigotes are incubated with components of t...
ORGANISM(S): Trypanosoma cruzi 
2020-06-17 | GSE140245 | GEO
UnknownDesign of a Protein Motif Responsive to Tyrosine Nitration and an Encoded Turn-Off Sensor of Tyrosine Nitration.
Not available
S-EPMC6688601 | biostudies-literature
UnknownElectrochemical Nitration with Nitrite.
Not available
S-EPMC9298355 | biostudies-literature
GenomicsGlobal changes in nitration levels and DNA binding profile of Trypanosoma cruzi histones induced by incubation with host extracellular matrix
Global changes in nitration levels and DNA binding profile of Trypanosoma cruzi histones induced by incubation with host extracellular matrix
PRJNA589041 | ENA
UnknownNitration of Hsp90 induces cell death.
Not available
S-EPMC3607042 | biostudies-literature
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