Nitric oxide synthase

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Unknown (5405)
Transcriptomics (374)
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Mus musculus (141)
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Organisms

Mus musculus (72)
Homo sapiens (35)
Rattus norvegicus (6)
Arabidopsis thaliana (2)
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Staphylococcus aureus subsp. aureus USA300_FPR3757 (1)
Mycobacterium tuberculosis str. Erdman = ATCC 35801 (1)
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Repository

biostudies-arrayexpress (274)
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geo (128)
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Tissue

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Endothelium (1)
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Disease

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Technology Type

Mass Spectrometry (40)
Shotgun proteomics (20)
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Mass spectrometry (7)
Mass spectrometry assay (5)
Affinity purification coupled with mass spectrometry proteomics (5)
Data-dependent acquisition (5)
Chemical cross-linking coupled with mass spectrometry proteomics (4)
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NextSeq 500, ILLUMINA (1)
Top-down proteomics (1)

Instrument Platform

Illumina HiSeq 2000 (8)
ScanArray 5000 [PerkinElmer] (5)
Illumina NovaSeq 6000 (4)
GenePix 4000B [Axon Instruments] (3)
Illumina HiSeq 3000 (3)
Illumina HiSeq 2500 (2)
Orbitrap Eclipse (2)
Orbitrap Fusion Lumos (2)
Q Exactive HF (2)
Liquid Chromatography MS - negative - hydrophilic-interaction-liquid-chromatography (2)
Liquid Chromatography MS - positive - reverse-phase (2)
Liquid Chromatography MS - negative - reverse-phase (2)
Qiagen RNAeasy, Bioanalyzer QubitFluorometer, Agilent 2100, RNA Pico 6000 chip (1)
(Make:PerkinElmer,Model:ScanArray 4000XL) (1)
Axon GenePix 4000A scanning hardware (1)
ScanArray [PerkinElmer] (1)
GenePix Professional 4200A [Axon Instruments] (1)
G2565AA DNA microarray scanner [Agilent] (1)
Illumina NovaSeq X (1)
Illumina HiSeq X (1)
DNBSEQ-G400 (1)
NextSeq 500 (1)
Xevo Q-Tof (1)
LTQ (1)
LTQ XL (1)
Q Exactive (1)
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Q Exactive Plus (1)
Thermo Q-Exactive Plus (1)
TripleTOF 5600+ (1)

Publication Date

2010 (48)
2008 (36)
2015 (33)
2011 (33)
2024 (32)
2026 (32)
2016 (25)
2013 (25)
2014 (24)
2025 (24)
2012 (23)
2007 (19)
2018 (18)
2021 (16)
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2022 (15)
2005 (14)
2009 (14)
2020 (10)
2019 (10)
2017 (10)
2006 (7)
2004 (1)

UNIPROT ID/AC

Q03135 (3)
P31749 (3)
P08238 (2)
Q9Y5W3 (2)
Q15119 (2)
O14733 (2)
P62158 (2)
Q05397 (2)
P45983 (2)
P01112 (2)
P29353 (2)
P60484 (2)
O15530 (2)
Q13233 (2)
Q07889 (2)
P12931 (2)
P62993 (2)
P29476 (1)

ENSEMBL ID

ENST00000297494 (1)

CHEBI ID

CHEBI:16480 (4)
CHEBI:16467 (4)
CHEBI:29108 (3)
CHEBI:16349 (3)
CHEBI:17858 (3)
CHEBI:15741 (3)
CHEBI:16704 (3)
CHEBI:30769 (3)
CHEBI:57600 (2)
CHEBI:203600 (2)
CHEBI:29034 (2)
CHEBI:29033 (2)
CHEBI:18348 (2)
CHEBI:15379 (2)
CHEBI:17552 (2)
CHEBI:18211 (2)
CHEBI:29016 (2)
CHEBI:28229 (2)
CHEBI:25682 (2)
CHEBI:17634 (2)
CHEBI:16264 (2)
CHEBI:15414 (2)
CHEBI:15753 (2)
CHEBI:16708 (2)
CHEBI:17562 (2)
CHEBI:17632 (1)
CHEBI:47830 (1)
CHEBI:17627 (1)
CHEBI:18009 (1)
CHEBI:16474 (1)

Metabolite Name

Histidine (3)
Valine (3)
Arginine (3)
Proline (3)
Phenylalanine (3)
Cytidine (3)
Anserine (2)
Glutamate (2)
Leucine (2)
Norleucine (2)
Glycine (2)
Betaine (2)
Carnosine (2)
Glutathione (2)
Carnitine (2)
Choline (2)
Lysine (2)
Asparagine (2)
4-Guanidinobutyric acid (2)
Tyrosine (2)
Adenosine (2)
Alanine (2)
Isoleucine (2)
Guanosine (2)
N-acetyl-D-mannosamine 6-phosphate (1)
3-keto-L-gulonic acid (1)
1,3-bisphospho-D-glyceric acid (1)
Cytidine diphosphate-choline (1)
Methylcytidine (1)
AlphaAminoIsoButyrate (1)

First Public Date

2014 (30)
2024 (27)
2026 (24)
2025 (17)
2021 (9)
2022 (7)
2019 (7)
2018 (7)
2017 (7)
2020 (6)
2015 (6)
2023 (5)
2016 (3)
2013 (3)

Modelling Approach

Ordinary differential equation model (13)

Lab affiliation

CRUK -CRUK Scotland nstitute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (2)
Faculty of Biology, Technion (2)
Institute for Transformative Molecular Medicine and Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA (2)
Roswell Park Cancer Center Buffalo, NY, USA (2)
1 Department of Anaesthesiology, LMU University Hospital, Ludwig-Maximilian-University (LMU), Munich, Germany 2 Walter Brendel Center of Experimental Medicine, Research Unit Immune Function and Immune Metabolism, Ludwig-Maximilian-University (LMU), Munich, Germany (1)
Advanced Clinical Biosystems Research Institute, Department of Medicine and The Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, United States (1)
Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, 37077 Göttingen, Germany Bioanalytics Group, Institute of Clinical Chemistry, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany (1)
Biotechnology Department, Proteomics Laboratory, BRFAA, Athens, Greece (1)
Cutaneous Oncology and Immunology Moffitt Cancer Center Tampa, FL, USA (1)
Department of Biomedicine, Aarhus University, Aarhus, Denmark (1)
Department of Cell Biology, Microbiology, and Molecular Biology University of South Florida Tampa, FL USA (1)
Department of Laboratory Medicine and Pathology Mayo Clinic 200 First Street SW Rochester, MN 55905, USA (1)
Department of Microbiology, Immunology and Cancer Biology and the Carter Immunology Center, School of Medicine, University of Virginia, USA. (1)
Department of Molecular Physiology and Biological Physics University of Virginia School of Medicine Charlottesville, VA, USA 22908 (1)
Department of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Avenida Lineu Prestes 1374, Room 9, Butanta, Sao Paulo (1)
Department of Pharmacology, University of Michigan (1)
Department of Redox Molecular Medicine, Tohoku University Graduate School of Medicine (1)
Head of Discovery Proteomics Facility, Oxford (1)
Heart and Diabetes Center NRW, Bad Oeynhausen University Hospital of the Ruhr-Universität Bochum (1)
Institute for Transformative Molecular Medicine, Case Western Reserve University School of Medicine (1)
Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany (1)
Institute of Medical Science, University of Toronto (1)
Jagiellonian University Medical College (1)
Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium (1)
Mass spectrometry facility, Functional Proteomics, SFB 815 Core Unit, Goethe-Universität, Frankfurt am Main, Germany (1)
New Drug Safety Evaluation Center, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China; NMPA Key Laboratory for Safety Research and Evaluation of Innovative Drug, Beijing 102206, China; Beijing Union -Genius Pharmaceutical Technology Development Co. Ltd., Beijing 100176, China (1)
Professor of Genetics and Complex Diseases, Harvard University T.H. Chan School of Public Health Professor of Cell Biology, Harvard Medical School Associate Member, Broad Institute of MIT and Harvard (1)
Research Institute for Complex Issues of Cardiovascular Diseases (1)
Research Unit in Environmental and Evolutionary Biology (URBE), Institute of Life, Earth & Environment, University of Namur (UNamur), 5000 Namur, Belgium (1)
Target Discovery Institute University of Oxford (1)

IsPrivate

False (13)

Model Flag

Non Miriam (5)

Classification

bacteria (5)
protozoa (1)

Study type

Transcription profiling by array (206)
RNA-seq of coding RNA (13)
Comparative genomic hybridization by array (10)
ChIP-seq (10)
Unknown experiment type (8)
ChIP-chip by tiling array (5)
Other (5)
Transcription profiling by RT-PCR (3)
ChIP-chip by array (2)
DNA-seq (2)
Methylation profiling by array (2)
RNA-seq of coding RNA from single cells (2)
RNA-seq of total RNA (2)
Tiling path by array (1)
Animal - High-throughput sequencing (1)
Genotyping by array (1)
MicroRNA profiling by array (1)

Release Date

2022 (493)
2020 (478)
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2023 (413)
2019 (369)
2017 (334)
2018 (328)
2016 (312)
2015 (312)
2014 (297)
2025 (278)
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2011 (211)
2012 (210)
2013 (197)
2010 (174)
2009 (132)
2008 (123)
2007 (61)
2026 (50)
2005 (44)
2006 (38)
2004 (23)
2001 (18)
2002 (15)
2000 (15)
2003 (9)
1999 (6)
1997 (6)
1998 (5)

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The vitamin D receptor and inducible nitric oxide synthase associated pathways in the development of acquired resistance to Cooperia oncophora infection in cattle

Cooperia oncophora is an economically important gastrointestinal nematode in ruminants. Acquired resistance to Cooperia oncophora infection in cattle develops rapidly as a result of prior infections. Naïve cattle, when given a primary infection of high-dose infective L3 larvae, develop a strong immu...

ORGANISM(S): Bos taurus

2011-09-28 | E-GEOD-24402 | biostudies-arrayexpress

Transcription profiling of Cd-induced nitric oxide synthesis in Arabidopsis

Cadmium treatment induces slow but long lasting nitric oxide production in plant tissues. This NO production can be suppressed using the commonly used Nitric Oxide Synthase inhibitor L-NAME. This inhibitor tends to partially alleviate Cd toxicity. This effect is correlated with a strong diminution o...

ORGANISM(S): Arabidopsis thaliana

2007-12-08 | E-MEXP-508 | biostudies-arrayexpress

Oleic acid-dependent modulation of Nitric Oxide Associated 1 protein levels regulate nitric oxide mediate signaling in plant defense.

Oleic acid-dependent modulation of Nitric Oxide Associated 1 protein levels regulate nitric oxide- mediate signaling in plant defense. Nitric Oxide, Oleic acid, Salicylic acid, Arabidopsis, Defense Wild-type Col-0, mutant genotypes ssi2, ssi2 act1 and ssi2 sid2 with three biological replicates were...

ORGANISM(S): Arabidopsis thaliana

2012-07-31 | E-GEOD-36797 | biostudies-arrayexpress

Transcription profiling of mice heart tissue treated with tetrahydrobiopterin compounds

Tetrahydrobiopterin compounds prolong allograft survival independent of their effect on nitric oxide synthase activity

ORGANISM(S): Mus musculus

2007-12-04 | E-GEOD-1809 | biostudies-arrayexpress

Inhibition of Respiration by Nitric Oxide Induces a Mycobacterium tuberculosis Dormancy Program

An estimated two billion persons are latently infected with Mycobacterium tuberculosis. The host factors that initiate and maintain this latent state and the mechanisms by which M. tuberculosis survives within latent lesions are compelling but unanswered questions. One such host factor may be nitric...

ORGANISM(S): Mycobacterium tuberculosis

2007-08-21 | E-GEOD-8839 | biostudies-arrayexpress

Nitric oxide synthase interactome

Identify the proteins interacting with human nitric oxide synthases

ORGANISM(S): Homo sapiens (Human)

2023-06-01 | PXD040726 | Pride

Nitric oxide synthase Interaction

Dissecting physiological and transcriptional responses of nitric oxide to drought stress by increasing in vivo nitric oxide content in Arabidopsis

Nitric oxide (NO) is involved in all major environmental stresses. However, most of these understandings were mainly based on pharmacological study using NO modulator compounds. Recently, our studies together with others provided a new class of plant experimental system with specific in vivo NO rele...

ORGANISM(S): Arabidopsis thaliana

2014-06-03 | E-GEOD-48474 | biostudies-arrayexpress

Transcriptome response to nitric oxide in Pseudomonas aeruginosa

DNA microarray analysis was employed to investigate the transcriptome response to nitric oxide in Pseudomonas aeruginosa. We focused on the role played by the nitric oxide-response regulators DNR and FhpR and an oxygen-response regulator ANR in the response. The transcriptome profiles of the P. aeru...

ORGANISM(S): Pseudomonas aeruginosa

2014-12-08 | E-GEOD-58862 | biostudies-arrayexpress

Global transcriptomic profiling of nitric oxide-mediated neuronal death

Nitric oxide (NO) is implicated in the pathogenesis of various neuropathologies characterised by oxidative stress. NO has been reported to be involved in the exacerbation of oxidative stress by various mechanisms, including protein modification, genotoxic damage and elevated production of reactive o...

ORGANISM(S): Mus musculus

2013-01-23 | E-GEOD-22087 | biostudies-arrayexpress

Role of nitric oxide and nitric oxide synthase isoforms in pulmonary emphysema.

PRJNA691047 | ENA

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