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TranscriptomicsExpression data from Rad21 knock-down in ES cells
The Cohesin complex has recently been described to regulate gene expression. We wanted to determine the gene expression profile specific in mouse ES cells after depletion of the Cohesin subunit Rad21. We used microarrays to detail the global programme of gene expression underlying depletion of Rad21...
ORGANISM(S): Mus musculus 
2011-05-19 | E-GEOD-23923 | biostudies-arrayexpress
TranscriptomicsThe Cohesin Complex Cooperates with Pluripotency Transcription Factors in the Maintenance of Embryonic Stem Cell Identity
Embryonic stem cells (ESCs) cells run a self-renewal gene expression program, requiring the expression of certain transcription factors accompanied by a particular chromosome organization to maintain a balance between pluripotency and the capacity for rapid differentiation. However, how transcriptio...
ORGANISM(S): Mus musculus 
2011-05-19 | E-GEOD-24030 | biostudies-arrayexpress
GenomicsGenome-wide maps of Rad21 in R1/E embryonic stem cells and R1/E derived Embryoid bodies
ChIP-seq based determination of Rad21 binding sites in embryonic stem cells (ESC) and ESC derived Embryoid Bodies (EB) identified Examination of Rad21 binding sites in 2 cell types
ORGANISM(S): Mus musculus 
2011-05-19 | E-GEOD-24029 | biostudies-arrayexpress
GenomicsGenome-wide maps of CTCF in R1/E embryonic stem cells
ChIP-seq based determination of CTCF binding sites in embryonic stem cells (ESC) Examination of CTCF binding sites
ORGANISM(S): Mus musculus 
2011-05-19 | E-GEOD-25777 | biostudies-arrayexpress
ProteomicsFemale mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema
Paladin (Pald1, mKIAA1274 or x99384) was identified in screens for vascular-specific genes and is a putative phosphatase. We have demonstrated that paladin has a predominant vascular expression pattern and shifts from endothelial to mural cells during mouse development. We have now characterized the...
ORGANISM(S): Mus Musculus (mouse) 
2017-11-01 | PXD005625 | JPOST Repository
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