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TranscriptomicsTranscriptional profiles of psychostimulant reinforcement in rats
Drug-induced alterations in transcriptional regulation play a central role in establishing the persistent neuroplasticities that occur during drug addiction. Additionally, changes in gene expression associated with drug administration provide valuable insight into the molecular basis of drug abuse. ...
ORGANISM(S): Rattus norvegicus 
2013-06-27 | E-GEOD-43748 | biostudies-arrayexpress
TranscriptomicsGene expression profile of human epidermal keratinocytes in response to IFNgamma, IL-4, IL-6, IL-17A and IL-22
To understand the role of epidermal keratinocytes in immunopathology of skin diseases with predominant T helper (Th) cell responses, we measured the genome-wide transcriptional profile of human keratinocytes in response to IFNgamma, IL-4, IL-17A or IL-22, major cytokines produced by Th1, Th2, Th17 o...
ORGANISM(S): Homo sapiens 
2014-10-02 | E-GEOD-53751 | biostudies-arrayexpress
TranscriptomicsAsymmetric self-renewal associated (ASRA) genes
Cell lines geneticially engineered to undergo conditional asymmetric self-renewal were used to identify genes whose expression is asymmetric self-renewal associated (ASRA). Non-random sister chromatid segregation occurs concordantly with asymmetric self-renewal in these cell lines. Asymmetric self-...
ORGANISM(S): Mus musculus 
2010-12-22 | E-GEOD-25334 | biostudies-arrayexpress
TranscriptomicsNovel biomarkers for distributed stem cells: asymmetric self-renewal associated (ASRA) genes identification by combined cDNA micro-array orthogonal intersection and sparse feature analysis
Biomarkers unique for distributed stem cells (DSCs) have proven elusive. Previous searches for proteins expressed specifically in DSCs were hampered by difficulty obtaining pure DSCs and challenges to successfully mining complex molecular expression data. To identify novel candidates for DSC bioma...
ORGANISM(S): Mus musculus 
2014-06-30 | E-GEOD-40183 | biostudies-arrayexpress
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