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TranscriptomicsThe regulon of the pleiotropic transcription factor Spx in Bacillus subtilis
The transcriptional regulator Spx plays a key role in maintaining the redox homeostasis of Bacillus subtilis cells exposed to disulfide stress. Defects in Spx were previously shown to lead to differential expression of numerous genes but direct and indirect regulatory effects could not be distinguis...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2012-09-06 | E-GEOD-35097 | biostudies-arrayexpress
ProteomicsListeria infection in hepatocytes
Listeria monocytogenes causes severe foodborne illness in pregnant women and immunocompromised individuals. After the intestinal phase of infection, the liver plays a central role in the clearance of this pathogen through its important functions in immunity. However, recent evidence suggests that su...
ORGANISM(S): Listeria monocytogenes EGD 
2021-11-02 | PXD027154 | Pride
Hepatocytes Listerai monocytogenes Lc-ms/ms 
TranscriptomicsConstitutive stringent response restores viability of Bacillus subtilis lacking Structural Maintenance of Chromosome protein
Bacillus subtilis mutants lacking the SMC-ScpAB complex are severely impaired for chromosome condensation and partitioning, DNA repair, and cells are not viable under standard laboratory conditions. We isolated suppressor mutations that restored the capacity of a smc deletion mutant (Δsmc) to grow u...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2015-09-23 | E-GEOD-73315 | biostudies-arrayexpress
TranscriptomicsPhosphorylation of Bacillus subtilis gene regulator AbrB modulates its DNA-binding properties
AbrB is a global gene regulator involved in transition phase phenomena in Bacillus subtilis. It participates in a complex regulatory network governing the expression of stationary phase functions. AbrB was previously found to be phosphorylated on serine 86 located close to its C-terminal oligomeriza...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2014-04-11 | E-GEOD-56723 | biostudies-arrayexpress
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