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Heart failure is a leading cause of death worldwide, and patients with severe heart failure require left ventricular assist device (LVAD) support. LVAD is usually implanted as a bridge to transplantation (BTT) or destination but can be removed if the patient’s cardiac function recovers. We performed...
ORGANISM(S): Homo sapiens (Human) 
2026-08-21 | PXD082534 | Pride

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7252 | MetaboLights

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights
IL28B genotype was shown to be associated with treatment outcome of antiviral thearpy for HCV infection. We tried to clarify the molecular feature that was associated with IL2B genotype by comparing Hepatic gene expression of HCV related Hepatocellular carcinoma and non-cancerous tissue with Il28B r...
ORGANISM(S): Homo sapiens 
Cysteine and lysine chemoproteomic profiling of Ophiobolin A
ORGANISM(S): Homo sapiens (Human) 
2023-12-12 | PXD047763 | Pride
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