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MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAMPT targeted therapy)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7252 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAD targeted time-course)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights
UnknownA 12-year epidemiological study of Acinetobacter baumannii from blood culture isolates in a single tertiary-care hospital using polymerase chain reaction (PCR)-based open reading frame typing.
Not available
S-EPMC9726563 | biostudies-literature
UnknownMultifaceted analysis of cross-tissue transcriptomes reveals phenotype-endotype associations in atopic dermatitis.
Not available
S-EPMC10545679 | biostudies-literature
UnknownRole of plasma angiogenesis factors in the efficacy of first-line chemotherapy combined with biologics in RAS wild-type metastatic colorectal cancer: Results from the GI-SCREEN CRC-Ukit study.
Not available
S-EPMC10557901 | biostudies-literature
UnknownHistopathological factors affecting the extraction of high quality genomic DNA from tissue sections for next-generation sequencing.
Not available
S-EPMC6759515 | biostudies-literature
UnknownRegulation of MEK inhibitor selumetinib sensitivity by AKT phosphorylation in the novel BRAF L525R mutant.
Not available
S-EPMC10119053 | biostudies-literature
UnknownCirculating tumor DNA-guided treatment with pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer: a phase 2 trial.
Not available
S-EPMC8604726 | biostudies-literature
ProteomicsCmDnm1, in vitro phosphorylation by CmAUR
Recombinant Cyanidioschyzon Dnm1 protein (CmDnm1) was incubated with recombinant Cyanidioschyzon Aurora kinase (CmAUR). Proteins were tryptic digested and the phosphorylated peptides were concentrated with Titansphere Phos -TiO Kit. Finally, the enriched peptides were analyzed by LC-MS.
ORGANISM(S): Cyanidioschyzon Merolae 
2019-12-27 | PXD013717 | JPOST Repository
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