Nonribosomal peptide

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Unknown (853)
Transcriptomics (293)
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Organisms

Homo sapiens (215)
Mus musculus (33)
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synthetic construct (1)
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Organisms

Bacillus cereus (2)
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Pseudovibrio brasiliensis (1)
Methylobacter tundripaludum 21/22 (1)
Pseudomonas [fluorescens] SBW25 (1)
Streptomyces canus (1)
Micromonospora okii (1)
Microtetraspora (1)
Kosakonia cowanii (1)
Penicillium chrysogenum (1)
Herbidospora (1)
synthetic construct (1)
Bacillus velezensis (1)
Staphylococcus aureus (1)
sponge metagenome (1)
soil metagenome (1)

Repository

biostudies-arrayexpress (287)
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pride (3)
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Tissue

Cell culture (1)
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Disease

Chronic lymphocytic leukemia (2)
Normal (2)
Prostate carcinoma lymph node metastasis (1)
Untreated prostate cancer (1)
Lung large cell carcinoma (1)
Cancer (1)
Prostate carcinoma (1)
Ewing's sarcoma (1)

Technology Type

Mass Spectrometry (3)
Shotgun proteomics (3)
Mass spectrometry (2)

Instrument Platform

Orbitrap Eclipse (6)
UltrafleXtreme (4)
6530 Accurate-Mass Q-TOF (Agilent instrument) (2)
Agilent microarray Scanner (1)
Agilent Microarray Hybridization Chamber Kit and Hybridization oven rotator (1)
Agilent miRNA Complete Labeling and Hyb Kit (1)
Extraction kit (1)
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Agilent Microarray scanner (G2505C) (1)
Illumina NovaSeq 6000 (1)
Illumina HiSeq 4000 (1)
Agilent 1290 Infinity II LC System (Agilent Technologies) coupled with a qTOF 6550 mass detector (1)
Q Exactive (1)
Xevo G2 XS Tof (1)
Agilent 6520 QTOF (1)
Liquid Chromatography MS - (1)

Publication Date

2014 (63)
2013 (59)
2010 (35)
2012 (34)
2015 (29)
2011 (24)
2016 (23)
2021 (11)
2018 (6)
2023 (5)
2009 (5)
2019 (4)
2008 (4)
2017 (3)
2022 (2)
2025 (2)
2024 (2)

CHEBI ID

CHEBI:137423 (1)
CHEBI:137422 (1)
CHEBI:137421 (1)
CHEBI:137420 (1)
CHEBI:137418 (1)
CHEBI:137417 (1)
CHEBI:137416 (1)
CHEBI:137414 (1)
CHEBI:137413 (1)
CHEBI:167190 (1)
CHEBI:167189 (1)
CHEBI:167188 (1)
CHEBI:167187 (1)
CHEBI:167186 (1)
CHEBI:167185 (1)

Metabolite Name

(E,Z)-N~2~,N~6~-bis[(3R)-1-hydroxy-3-isocyanododecylidene]-L-lysine (1)
(E,Z)-N~2~,N~6~-bis[(3R)-1-hydroxy-3-isocyanodecylidene]-L-lysine (1)
(3R)-3-[(carboxymethyl)amino]decanoic acid (1)
(1Z)-N-{(5S)-6-hydroxy-5-[(E)-(1-hydroxydecylidene)amino]hexyl}decanimidic acid (1)
(1Z,3R)-N-[(5S)-6-hydroxy-5-{(E)-[(3R)-1-hydroxy-3-isocyanobutylidene]amino}hexyl]-3-isocyanobutanimidic acid (1)
(1Z,3R)-N-[(5S)-6-(acetyloxy)-5-{(E)-[(3R)-1-hydroxy-3-isocyanobutylidene]amino}hexyl]-3-isocyanobutanimidic acid (1)
(3R)-3-[(carboxymethyl)amino]butanoic acid (1)
(1Z)-N-{(5S)-6-hydroxy-5-[(E)-(1-hydroxyhexylidene)amino]hexyl}hexanimidic acid (1)
(1Z)-N-{(5S)-6-hydroxy-5-[(E)-(1-hydroxybutylidene)amino]hexyl}butanimidic acid (1)
2,2',2''-((2R,5R,8S,11R)-11-((2R,4S,5E,7E,9E)-2,4-dihydroxypentadeca-5,7,9-trien-1-yl)-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-2,5,8-triyl)triacetamide (1)
(3R,5R,7S,8E,10E,12E)-3-amino-5,7-dihydroxyoctadeca-8,10,12-trienoic acid (1)
(3-((3R,5R,7S,8E,10E,12E)-3-amino-5-hydroxy-7-methoxyoctadeca-8,10,12-trienamido)propanoyl)-D-asparaginyl-D-asparagine (1)
(3-((3R,5R,7S,8E,10E,12E)-3-amino-5-hydroxy-7-methoxyoctadeca-8,10,12-trienamido)propanoyl)-D-asparagine (1)
3-((3R,5R,7S,8E,10E,12E)-3-amino-5-hydroxy-7-methoxyoctadeca-8,10,12-trienamido)propanoic acid (1)
(3R,5R,7S,8E,10E,12E)-3-amino-5-hydroxy-7-methoxyoctadeca-8,10,12-trienoic acid (1)

First Public Date

2026 (6)
2016 (4)
2017 (3)
2014 (3)
2023 (2)
2020 (2)
2015 (2)
2025 (1)
2024 (1)
2022 (1)
2021 (1)

Classification

bacteria (4)

Study type

Transcription profiling by array (254)
MicroRNA profiling by array (19)
RNA-seq of coding RNA (4)
Human - One-color microarray (2)
Other (2)
RNA-seq of non coding RNA (2)
Animal - One-color microarray (1)
ChIP-chip by tiling array (1)
ChIP-chip by array (1)
Comparative genomic hybridization by array (1)

Release Date

2014 (105)
2013 (86)
2012 (73)
2016 (69)
2010 (66)
2015 (64)
2020 (62)
2023 (57)
2021 (57)
2018 (57)
2022 (56)
2019 (55)
2017 (53)
2025 (51)
2011 (50)
2024 (35)
2009 (31)
2008 (24)
2006 (22)
2007 (20)
2005 (11)
2004 (11)
2026 (6)
2003 (6)
2002 (5)
2001 (4)
1998 (2)
2000 (1)
1999 (1)

Lab affiliation

(Monash University). Y. T. Candace Ho: yee.ho@monash.edu (Monash University) (1)
Department of Biology, Maynooth University, Co. Kildare, Ireland (1)
Department of Microbiology and Immunology University of California, San Francisco (UCSF) USA (1)

Tags

pathogen (4)
pathogen:bacterium (4)
xref:PubMed:39727420 (1)
xref:PubMed:23864577 (1)
xref:PubMed:24884713 (1)
xref:PubMed:20522739 (1)
xref:PubMed:36998231 (1)

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Mapping the biosynthetic pathway of a hybrid polyketide-nonribosomal peptide in a metazoan

Polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) hybrid systems typically use complex protein-protein interactions to facilitate direct transfer of intermediates between these multimodular megaenzymes. In the canal-associated neurons (CANs) of Caenorhabditis elegans, PKS-1 and NR...

2021-06-22 | MTBLS2313 | MetaboLights

Biosynthesis of Isonitrile Lipopeptides by Conserved Non-ribosomal Peptide Synthetase Gene Clusters in Actinobacteria

A putative lipopeptide biosynthetic gene cluster is conserved in many species of Actinobacteria, including Mycobacterium tuberculosis and Mycobacterium marinum, but the specific function of the encoding proteins has been elusive. Using both in vivo heterologous reconstitution and in vitro biochemica...

2017-07-18 | MTBLS454 | MetaboLights

Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence

Staphylococcus aureus is a major human pathogen and resistant to numerous clinically used antibiotics. The first antibiotic developed for S. aureus infections was the nonribosomal petide secondary metabolite penicillin. We discovered cryptic nonribosomal peptide secondary metabolites, the aureusimi...

ORGANISM(S): Staphylococcus aureus

2010-07-30 | E-GEOD-21373 | biostudies-arrayexpress

Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence

ORGANISM(S): Staphylococcus aureus

2010-07-01 | GSE21373 | GEO

Staphylococcus aureus

Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence

PRJNA126083 | ENA

Nonribosomal peptide synthesis and toxigenicity of cyanobacteria.

Not available

S-EPMC93901 | biostudies-literature

Guidelines for Optimizing Type S Nonribosomal Peptide Synthetases.