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ProteomicsEffect of Nop53 depletion on the exosome interactome
In order to evaluate how Nop53 modulates the interaction of Rrp6 and Rrp43 with other factors, a coimmunoprecipitation assay was performed both in the presence (-doxicycline) and upon depletion (+ doxicycline) of Nop53 using the condional strain Δnop53/tetOff::GFP-NOP53 carrying the Rrp6-TAP or Rrp4...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-08 | PXD014187 | Pride
Nop53 Rrna processing Rna exosome Ribosome biogenesis 
ProteomicsEffect of Nop53 depletion on the compositional changes during pre-60S maturation
The eukaryotic ribosome biogenesis is a highly orchestrated multistep process that starts at the nucleolus with the transcription of pre-rRNAs 5S and 35S. The latter comprises the mature 18S, 5.8S and 25S rRNAs separated by internal transcribed spacers (ITS1 and ITS2) and externally flanked by the 5...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-09 | PXD023383 | Pride
Nop53 Eukaryotic ribosome biogenesis Pre-60s S. cerevisiae 
UnknownNOP53 undergoes liquid-liquid phase separation and promotes tumor radio-resistance.
Not available
S-EPMC9622906 | biostudies-literature
UnknownCytoplasmic Translocation of Nucleolar Protein NOP53 Promotes Viral Replication by Suppressing Host Defense.
Not available
S-EPMC5923502 | biostudies-literature
UnknownThe ribosome assembly factor Nop53 controls association of the RNA exosome with pre-60S particles in yeast.
Not available
S-EPMC6916480 | biostudies-literature
UnknownStructural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
Not available
S-EPMC5688999 | biostudies-literature
UnknownThe ribosome assembly factor Nop53 has a structural role in the formation of nuclear pre-60S intermediates, affecting late maturation events.
Not available
S-EPMC8266606 | biostudies-literature
UnknownThe HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response.
Not available
S-EPMC7564582 | biostudies-literature
UnknownStudies on the assembly characteristics of large subunit ribosomal proteins in S. cerevisae.
Not available
S-EPMC3707915 | biostudies-literature
UnknownAtomic modeling of the ITS2 ribosome assembly subcomplex from cryo-EM together with mass spectrometry-identified protein-protein crosslinks.
Not available
S-EPMC5192979 | biostudies-literature
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