Sort   by:  
 Page size 
Background: The goal of this study was to determine the transcriptional consequences of norepinephrine transporter (NET) gene deletion in noradrenergic neuron differentiation. The norepinephrine transporter (NET) is the target of powerful mind-altering substances, such as tricyclic antidepressants a...
ORGANISM(S): Mus musculus 
RNA-seq analysis of differentiated noradrenergic neurons (1C11NE) and microglia (BV2) following exposure to acrylamide (ACR)
Aims: This study aimed to identify and characterize the intrinsic properties of locus coeruleus (LC) noradrenergic neurons in male and female mice using a genetic approach. We also sought to investigate sex-specific differences in membrane properties, action potential generation, and protein express...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-24 | PXD045844 | Pride
Neurotoxicity of acrylamide (ACR), which is an environmental electrophilic chemical, has been reported in occupational human cases and experimental animal models. Our previous study using murine model demonstrated that exposure to ACR induced dose-dependent degeneration of noradrenergic axons, which...
ORGANISM(S): Mus musculus 
2025-10-16 | GSE197871 | GEO
Preclinical work has long focused only on male animals, even though sexual divergence in both baseline behaviors and drug responses clearly impact treatment outcomes in patients. Psychiatric disorders are notably divergent, with males showing higher prevalence of ADHD and ASD, and females GAD and MD...
ORGANISM(S): Mus musculus 
2018-04-30 | GSE100004 | GEO
Preclinical work has long focused only on male animals, even though sexual divergence in both baseline behaviors and drug responses clearly impact treatment outcomes in patients. Psychiatric disorders are notably divergent, with males showing higher prevalence of ADHD and ASD, and females GAD and MD...
ORGANISM(S): Mus musculus 
2018-04-30 | GSE100002 | GEO
Sort   by:  
 Page size