Sort   by:  
 Page size 
TranscriptomicsAlkbh1/Tzfp Repress a Non-Repeat piRNA Cluster in Pachytene Spermatocytes
Piwi proteins and Piwi-interacting small RNAs (piRNAs) have known functions in transposon silencing in the male germline of fetal and newborn mice. Both are also necessary for spermatogenesis in adult testes, however, their function here remains a mystery. Here, we use germ cell isolations and small...
ORGANISM(S): Mus musculus 
2012-09-11 | E-GEOD-37150 | biostudies-arrayexpress
TranscriptomicsTestis samples from Alkbh1 wild-type and KO mice
The aim of the study was to elucidate the role of Alkbh1 by targeted deletion in C57/BL6 mice. Alkb deficiency results in sex-ratio distortion of offspring and apoptosis in adult testes, most likely caused by defects in the pachytene stage during spermatogenesis. Due to the pivotal role of Alkbh1 in...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-22073 | biostudies-arrayexpress
Sort   by:  
 Page size