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MetabolomicsSingle-Cell and Spatial Multi-Omics Reveal Mechanical Stress Driving Heterogeneous Xylem Development in Populus [Spatial metabolomics_MALDI imaging]
Xylem, the predominant tissue for structural support, forms tension wood with G-layer-rich fibers under mechanical stress. Despite being recognized over a century ago, three key biological questions remained unclear: (1) Are fibers in normal and tension wood distinct cells due to morphological diffe...
2025-06-16 | MTBLS12601 | MetaboLights
TranscriptomicsMultiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes
The central nervous system normally functions at O2 levels which would be regarded as hypoxic by most other tissues. However, most in vitro studies of neurons and astrocytes are conducted under hyperoxic conditions without consideration of O2-dependent cellular adaptation. We analyzed the reactivi...
ORGANISM(S): Rattus norvegicus 
2012-09-20 | E-GEOD-29296 | biostudies-arrayexpress
MetabolomicsSingle-Cell and Spatial Multi-Omics Reveal Mechanical Stress Driving Heterogeneous Xylem Development in Populus [Spatial metabolomics_LCM]
Xylem, the predominant tissue for structural support, forms tension wood with G-layer-rich fibers under mechanical stress. Despite being recognized over a century ago, three key biological questions remained unclear: (1) Are fibers in normal and tension wood distinct cells due to morphological diffe...
2025-06-16 | MTBLS12561 | MetaboLights
TranscriptomicsTranscription profiling of human normal subjects and IPAH patients to examine the effect of BMP-2 on pulmonary artery smooth muscle cells
Bone morphogenetic proteins (BMP) inhibit proliferation and induce apoptosis in pulmonary artery smooth muscle cells (PASMC) from normal subjects. Dysfunction of BMP signaling due to mutations in and/or downregulation of BMP receptors has been implicated in idiopathic pulmonary arterial hypertension...
ORGANISM(S): Homo sapiens 
2007-09-07 | E-GEOD-2559 | biostudies-arrayexpress
ProteomicsSingle-Cell and Spatial Multi-Omics Reveal Mechanical Stress Driving Heterogeneous Xylem Development in Populus [Phosphoproteomics]
Xylem, the predominant tissue for structural support, forms tension wood with G-layer-rich fibers under mechanical stress. Despite being recognized over a century ago, three key biological questions remained unclear: (1) Are fibers in normal and tension wood distinct cells due to morphological diffe...
ORGANISM(S): Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa) 
2025-06-18 | PXD064017 | Pride
Mechanical stress Xylem development Tension wood Cell fate determination Lc-ms/ms Phosphoproteome Gravity sensing 
UnknownNormal-tension glaucoma: Pathogenesis and genetics.
Not available
S-EPMC6307418 | biostudies-literature
UnknownEffect of myopia on the progression of normal tension glaucoma.
Not available
S-EPMC10289344 | biostudies-literature
TranscriptomicsRole of zyxin in the tension-induced expression change in endothelial cells
One of the hallmarks in hypertension is a pressure-induced change in endothelial cell phenotype. A cytoskeletal protein zyxin, which was seen to translocate from focal adhesion contacts to the nucleus in response to the increased wall tensionis, mediates the tension-induced endothelial signaling. Mi...
ORGANISM(S): Homo sapiens 
2010-08-16 | E-GEOD-17814 | biostudies-arrayexpress
UnknownComparison of volumes of brain areas in patients with bilateral early high-tension and normal-tension glaucoma in 7 Tesla MRI.
Not available
S-EPMC12829933 | biostudies-literature
UnknownPeripapillary Vessel Density in Young Patients with Open-Angle Glaucoma: Comparison between High-Tension and Normal-Tension Glaucoma.
Not available
S-EPMC6914787 | biostudies-literature
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