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We screened for differentially expressed genes in the developing notochord using the Affymetrix microarray system in Xenopus laevis. At late gastrula, we dissected four regions from the embryo, anterior mesoderm, posterior mesoderm, notochord and presomitic mesoderm. Three types of comparison were c...
ORGANISM(S): Xenopus laevis 
Lumen formation and inflation are crucial for tubular organ morphogenesis, yet the underling mechanism remains largely unrevealed. Here, we applied 4D proteomics to screen the lumenogenesis-related proteins and reveal the potentially biological pathways that are involved in lumen inflation during no...
ORGANISM(S): Ciona savignyi 
2023-05-10 | PXD037089 | Pride
Expression data from chordoma and notochord (microarray)
A 37 kb region upstream of Brachyury comprising a notochord enhancer is essential for notochord and tail development
Expression data from chordoma and notochord (RNA-Seq)
A conserved notochord enhancer controls pancreas development in vertebrates
The notochord is the eponymous feature of the chordates and an essential organ in chordate development. The notochord of the invertebrate chordate Ciona consists of only 40 cells, and is a longstanding model for studying differentiation and morphogenesis in a small, simple embryo. Here we perform RN...
ORGANISM(S): Ciona intestinalis 
2017-09-19 | GSE95333 | GEO
Brachyury controls Ciona notochord fate as part of a feedforward network [I]
Spine patterning is guided by segmentation of the notochord sheath
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