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TranscriptomicsCoordinated Chromatin Remodeling induced by Demethylation requires SRCAP mediated H2A.Z exchange
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-26685 | biostudies-arrayexpress
TranscriptomicsCoordinated Chromatin Remodeling induced by Demethylation requires SRCAP mediated H2A.Z exchange [Methylation]
Genome wide DNA methylation profiling of RKO cells with combination treatments of non-target siRNA or SRCAP siRNA and PBS or 1uM 5-Aza-CdR treatment. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across 27,578 CpGs in treated RKO cells. Sam...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-26433 | biostudies-arrayexpress
TranscriptomicsCoordinated Chromatin Remodeling induced by Demethylation requires SRCAP mediated H2A.Z exchange [expression]
Genome wide gene expression profiling of RKO cells with combination treatments of non-target siRNA or SRCAP siRNA and PBS or 1uM 5-Aza-CdR treatment. The sample treated with non target siRNA and PBS serves as control sample. Total RNA obtained from isolated RKO cells.
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-26684 | biostudies-arrayexpress
TranscriptomicsIdentification of mesendoderm precursor- and neurectoderm precursor-enriched genes in Zebrafish embryos
We have developed a method for rapidly identifying early, regionally-expressed molecules: FACS-Assisted Microdissection of Photolabeled cells (FAM-P). For our first FAM-P project, we injected embryos with purified Kaede protein, a stony coral protein that fluoresces at 514 nm (green) prior to- and 5...
ORGANISM(S): Danio rerio 
2010-05-26 | E-GEOD-8654 | biostudies-arrayexpress
GenomicsGenome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion.
Runx2 is a metastatic transcription factor (TF) increasingly expressed during prostate cancer (PCa) progression. Using PCa cells conditionally expressing Runx2, we previously identified Runx2-regulated genes with known roles in epithelial-mesenchymal transition, invasiveness, angiogenesis, extracel...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-33889 | biostudies-arrayexpress
GenomicsEpigenetic Profiling of Human Colorectal Cancer

DNA methylation, together with chromatin modifications, constitute the epigenome that functions to regulate gene expression and genome integrity. DNA methylation alterations are ubiquitous in human cancers, as many genes acquire DNA methylation in a cancer-specific manner. DNA methylation at thes...

phs000385.v1.p1 | EGA
UnknownTCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data.
Not available
S-EPMC4856967 | biostudies-literature
UnknownMolecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.
Not available
S-EPMC4754110 | biostudies-literature
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