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ProteomicsBioID screen for NRF3 interactors in SCC13 and HaCaT cells
We identified the transcription factor NRF3 as an important tumor-suppressing protein in the skin. To gain insight into the mechanisms of action of NRF3 in keratinocytes, we searched for NRF3 interactors in the SCC13 skin cancer and the immortalized non-tumorigenic HaCaT cell line using BioID intera...
ORGANISM(S): Homo sapiens (Human) 
2023-10-09 | PXD043305 | Pride
Hacat cells Q-exactive hf Nrf3 Scc13 cells Bioid 
GenomicsExpression data from NRF3 knockdown or overexpression cells
Expression data from NRF3 knockdown or overexpression cells
PRJNA736301 | ENA
GenomicsDifferentially expressed genes in SCC13 NRF3-KO cells and SCC13 cells that re-express endogenous concentrations of recombinant NRF3
Differentially expressed genes in SCC13 NRF3-KO cells and SCC13 cells that re-express endogenous concentrations of recombinant NRF3
PRJNA941808 | ENA
GenomicsExpression data from NRF3 overexpression cells treated with forskolin
Expression data from NRF3 overexpression cells treated with forskolin
PRJNA825107 | ENA
TranscriptomicsDifferentially expressed genes in SCC13 NRF3-KO cells and SCC13 cells that re-express endogenous concentrations of recombinant NRF3
We identified a tumor-suppressing function of NRF3 in skin cancer. To determine the underlying mechanism of action we wanted to compare the transcriptome of SCC13 NRF3-KO cells and SCC13 cells that re-express endogenous concentrations of recombinant NRF3.
ORGANISM(S): Homo sapiens 
2023-10-09 | GSE226798 | GEO
TranscriptomicsExpression data from NRF3 knocked-down DLD-1 cells
Accumulated evidences suggest physiological relevance between the transcription factor NRF3 (NFE2L3) and cancers. However NRF3 target genes in cancer cells remain poorly understood. We used microarrays to identify to identify NRF3 taget genes which regulate cell proliferation.
ORGANISM(S): Homo sapiens 
2017-10-31 | GSE99080 | GEO
TranscriptomicsExpression data from NRF3 overexpression cells treated with forskolin
A CNC-family transcription factor, Nrf3, is highly expressed in the basal cell layer of the epidermis where melanocytes resident, although the melanogenic function of Nrf3 remains unclear. We used microarrays to identify NRF3-regulated gene expression network related to melanogenesis.
ORGANISM(S): Mus musculus 
2025-04-09 | GSE200537 | GEO
UnknownNRF3 activates mTORC1 arginine-dependently for cancer cell viability.
Not available
S-EPMC9932127 | biostudies-literature
TranscriptomicsExpression data from NRF3 knockdown or overexpression cells
The genetic association of a transcription factor NRF3 with obesity has been reported, although the molecular mechanisms remain unknown We used microarrays to identify NRF3-regulated gene expression network related to lipid metabolism.
ORGANISM(S): Homo sapiens 
2021-10-20 | GSE176444 | GEO
GenomicsNovel Roles of Nrf3-Trim5 Axis in Vascular Smooth Muscle Cell Dysfunctions and Neointimal Hyperplasia
Novel Roles of Nrf3-Trim5 Axis in Vascular Smooth Muscle Cell Dysfunctions and Neointimal Hyperplasia
PRJNA1186078 | ENA
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