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GenomicsRole of Nrg-1 in the development of heart ventricular chamber in mice.
Role of Nrg-1 in the development of heart ventricular chamber in mice.
PRJNA893658 | ENA
TranscriptomicsNRG1/ERBB3 signaling in melanocyte Melan-Ink4a cells
Neuregulin (NRG) signaling through the receptor tyrosine kinase, ERBB3, is required for embryonic development, and dysregulated signaling has been associated with cancer progression. Here, we show that NRG1/ERBB3 signaling inhibits melanocyte (MC) maturation and promotes undifferentiated, migratory ...
ORGANISM(S): Mus musculus 
2010-05-07 | E-GEOD-21463 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of infarcted rats teated with rhNRG-1(recombinant human NRG-1)
The ErbB famliy of erceptor tyrosine kinases and their ligands, neuregulins(NRGs), are crtical involved not only in cardiac development but also in the maintenace of structural and functional integrity of the adult heart. rhNRG-1(recombinant human NRG-1) Improves cardiac function and sruvival in mod...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-9263 | biostudies-arrayexpress
TranscriptomicsRole of Nrg-1 in the development of heart ventricular chamber in mice.
To investigate the role of Nrg-1 in heart ventricular chamber development, we have used RNA-Seq to characterize the effect of Nrg-1 inactivation or over-expression in mouse embryos at E9.5 and E15.5. This SuperSeries is composed of the SubSeries listed below.
ORGANISM(S): Mus musculus 
2023-12-01 | GSE216471 | GEO
TranscriptomicsInfarcted rats teated with rhNRG-1(recombinant human NRG-1)
The ErbB famliy of erceptor tyrosine kinases and their ligands, neuregulins(NRGs), are crtical involved not only in cardiac development but also in the maintenace of structural and functional integrity of the adult heart. rhNRG-1(recombinant human NRG-1) Improves cardiac function and sruvival in mod...
ORGANISM(S): Rattus norvegicus 
2007-10-18 | GSE9263 | GEO
TranscriptomicsCharacterization of the effect of deleting the Nrg-1(neuregulin-1) gene, using the endothelial driver line Tie2-Cre in E (embryonic day) 9.5 hearts
To investigate the role of Nrg-1 in heart ventricular chamber development we deleted Nrg-1 in endothelial lineages, harvested hearts at E9.5, and determined gene expression profiles, using RNA-seq.
ORGANISM(S): Mus musculus 
2023-12-01 | GSE216470 | GEO
TranscriptomicsCharacterization of the effect of overexpressing the Nrg-1 (neuregulin-1) gene, using the cardiac driver line Nkx2.5-Cre, in E (embryonic day) 15.5 heart venticles
To investigate the role of Nrg-1 in heart ventricular chamber development, we overexpressed Nrg-1 in cardiac lineages, harvested ventricles at E15.5, and determined gene expression profiles, using RNA-seq.
ORGANISM(S): Mus musculus 
2023-12-01 | GSE216467 | GEO
TranscriptomicsCharacterization of the effect of deleting the Nrg-1(neuregulin-1) gene, using the tamoxifen-inducible endothelial driver line Cdh5-CreERT in E (embryonic day) 15.5 hearts
To investigate the role of Nrg-1 in heart ventricular chamber development, we induced a conditional Nrg-1 deletion in endothelial cells at E15.5, with tamoxifen, and determined gene expression profiles, using RNA-seq.
ORGANISM(S): Mus musculus 
2023-12-01 | GSE216469 | GEO
GenomicsCharacterization of the effect of deleting the Nrg-1(neuregulin-1) gene, using the endothelial driver line Tie2-Cre in E (embryonic day) 9.5 hearts
Characterization of the effect of deleting the Nrg-1(neuregulin-1) gene, using the endothelial driver line Tie2-Cre in E (embryonic day) 9.5 hearts
PRJNA893671 | ENA
GenomicsCharacterization of the effect of deleting the Nrg-1(neuregulin-1) gene, using the tamoxifen-inducible endothelial driver line Cdh5-CreERT in E (embryonic day) 15.5 hearts
Characterization of the effect of deleting the Nrg-1(neuregulin-1) gene, using the tamoxifen-inducible endothelial driver line Cdh5-CreERT in E (embryonic day) 15.5 hearts
PRJNA893669 | ENA
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