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UnknownThe Role of NSUN Family Genes in m5C Methylation and Diseases.
Not available
S-EPMC12731187 | biostudies-literature
GenomicsTranslational profiling reveals that mRNAs encoding cuticle collagens are translationally repressed upon nsun-1 knockdown
Translational profiling reveals that mRNAs encoding cuticle collagens are translationally repressed upon nsun-1 knockdown
PRJNA601121 | ENA
TranscriptomicsTranslational profiling reveals that mRNAs encoding cuticle collagens are translationally repressed upon nsun-1 knockdown
By comparing mRNAs contained in the polysome fraction to total mRNAs in Caenorhabditis elegans exposed to either RNAi control or nsun-1 RNAi, we found that loss of NSUN-1 translationally represses genes associated with collagens, cuticle integrity and development. These changes explain phenotypes of...
ORGANISM(S): Caenorhabditis elegans 
2020-12-09 | GSE143618 | GEO
UnknownThe ribosomal RNA m<sup>5</sup>C methyltransferase NSUN-1 modulates healthspan and oogenesis in <i>Caenorhabditis elegans</i>.
Not available
S-EPMC7746234 | biostudies-literature
UnknownMulti-omics analysis of expression and prognostic value of NSUN members in prostate cancer.
Not available
S-EPMC9376292 | biostudies-literature
GenomicsQuantitative Analysis of transcriptome in organoids derived from TP190 wildtype(WT) and Williams Syndrome(NSUN-GTF2ird2+/-) human induced Pluripotent Stem Cell
Quantitative Analysis of transcriptome in organoids derived from TP190 wildtype(WT) and Williams Syndrome(NSUN-GTF2ird2+/-) human induced Pluripotent Stem Cell
PRJNA800825 | ENA
GenomicsEpitranscriptomic maps of 5-methylcytosine reveal substrate diversity of NSUN methyltransferases and links to mRNA translation and turnover
Epitranscriptomic maps of 5-methylcytosine reveal substrate diversity of NSUN methyltransferases and links to mRNA translation and turnover
PRJNA1060300 | ENA
GenomicsRNA BS-seq of Nocodazole treated HeLa cells with NSUN family member deficiency
RNA BS-seq of Nocodazole treated HeLa cells with NSUN family member deficiency
PRJNA811505 | ENA
Methylation profilingDistinct NSun methylases control cytosine-5 methylation of messenger, mitochondrial and transfer RNA: implications for human diseases [miCLIP & Bisfulfite-Seq HEK293]
Aberrant post-transcriptional methylation is implicated in a wide range of human diseases, yet the specific enzymes responsible for site- and substrate-specific methylation remain largely unknown. Here, we use our recently developed catalysis-dependent RIP sequencing approach (miCLIP) and RNA bisulf...
ORGANISM(S): Homo sapiens 
2017-02-14 | GSE66011 | GEO
Methylation profilingDistinct NSun methylases control cytosine-5 methylation of messenger, mitochondrial and transfer RNA: implications for human diseases [Bisulfite-Seq dermal fibroblasts]
Aberrant post-transcriptional methylation is implicated in a wide range of human diseases, yet the specific enzymes responsible for site- and substrate-specific methylation remain largely unknown. Here, we use our recently developed catalysis-dependent RIP sequencing approach (miCLIP) and RNA bisulf...
ORGANISM(S): Homo sapiens 
2017-02-14 | GSE66010 | GEO
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